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Combined OCP may leads to higher pain improvement (assessed as improvement from 1 major category to… compared with placebo or no treatment (low certainty).
Combined OCP probably leads to higher adverse events compared with placebo or no treatment (moderate certainty).
Combined OCP may leads to lower requirement for additional medication compared with placebo or no treatment (low certainty).
Combined OCP may leads to lower absence from work or school compared with placebo or no treatment (low certainty).
Combined low‐dose OCP showed no clear difference in pain improvement compared with another combined low‐dose OCP (moderate certainty).
Combined low‐dose OCP may leads to higher adverse events for continuous vs standard regimen OCP compared with another combined low‐dose OCP (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
Local excision showed no clear difference in disease‐free survival (D‐FS)Â compared with radical resection (low certainty).
It is very uncertain whether local excision changes cancer‐related survival (C‐RS)Â compared with radical resection (very low certainty).
Local excision showed no clear difference in major postoperative complications compared with radical resection (low certainty).
Local excision probably leads to lower minor postoperative complications compared with radical resection (moderate certainty).
Clobetasol propionate cream probably leads to higher disease control (healing of skin lesions) at day 21 compared with oral prednisone (moderate certainty).
Doxycycline probably leads to lower treatment‐related mortality at 1 year (mITT) compared with prednisolone (moderate certainty).
Doxycycline probably leads to lower number of participants with grade 3‐4 (severe or life‐threatening)… compared with prednisolone (moderate certainty).