Sensitivity for detection of oral cavity cancer/OPMD · Apparently healthy adults not reporting symptoms of OPMD or OSCC, attending an organised screening or surveillance programme, or screened…
1 finding from 1 review
Summary of findings 1 (no pooled analysis): for the 7 studies with low prevalence (<=10%) sensitivity ranged from 0.50 (95% CI 0.07 to 0.93) to 0.99 (95% CI 0.97 to 1.00); for the 3 higher-prevalence studies…
10 studies · 25568 participants
Low
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
For resin-based bonding agents, fluoride release did not significantly change WSL initiation (RR 0.97); subgroup not separately GRADE-rated.
1 finding from 1 review
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
It is very uncertain whether sealing using sealant materials changes failure of therapy compared with non-selective carious tissue removal and conventional restoration (CR) (very low certainty).
1 finding from 1 review
Dental caries · Children with Down syndrome in Dubai
Mean DMFT was 2.73 in children with Down syndrome versus 1.65 in controls.
1 finding from 1 review
MEAN 2.73
1 study
GRADE not reported
Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
It is very uncertain whether sealing using sealant materials changes failure of therapy compared with no treatment (very low certainty).
1 finding from 1 review
Retention success rate · Children with primary molars requiring proximal (Class II) restorations
For the Rubber dam isolation: Yes subgroup, the 24-month retention success rate was 0.931 (95% CI 0.834-0.973; ungraded).
28 findings from 1 review
Proportion 0.931 [0.834, 0.973]
10 studies
GRADE not reported
Proportion 0.867 [0.779, 0.924]
24 studies
GRADE not reported
Proportion 0.805 [0.674, 0.892]
16 studies
GRADE not reported
Show 25 more findings
Proportion 0.934 [0.859, 0.971]
11 studies
GRADE not reported
Proportion 0.824 [0.672, 0.914]
8 studies
GRADE not reported
Proportion 0.554 [0.168, 0.885]
2 studies
GRADE not reported
Proportion 0.649 [0.488, 0.783]
8 studies
GRADE not reported
Proportion 0.950 [0.639, 0.995]
1 study
GRADE not reported
Proportion 0.879 [0.803, 0.928]
27 studies
GRADE not reported
Proportion 0.935 [0.726, 0.987]
3 studies
GRADE not reported
Proportion 0.904 [0.474, 0.989]
3 studies
GRADE not reported
Proportion 0.949 [0.868, 0.981]
7 studies
GRADE not reported
Proportion 0.826 [0.605, 0.937]
10 studies
GRADE not reported
Proportion 0.839 [0.764, 0.893]
34 (27 observed + 7 imputed) studies
GRADE not reported
Proportion 0.936 [0.895, 0.961]
19 studies
GRADE not reported
Proportion 0.854 [0.718, 0.931]
15 studies
GRADE not reported
Proportion 0.897 [0.792, 0.952]
12 studies
GRADE not reported
Proportion 0.956 [0.865, 0.986]
5 studies
GRADE not reported
Proportion 0.973 [0.695, 0.998]
2 studies
GRADE not reported
Proportion 0.851 [0.716, 0.929]
15 studies
GRADE not reported
Proportion 0.895 [0.828, 0.938]
25 studies
GRADE not reported
Proportion 0.899 [0.768, 0.961]
9 studies
GRADE not reported
Proportion 0.847 [0.726, 0.920]
14 studies
GRADE not reported
Proportion 0.854 [0.609, 0.956]
9 studies
GRADE not reported
Proportion 0.671 [0.447, 0.838]
6 studies
GRADE not reported
Proportion 0.892 [0.614, 0.977]
3 studies
GRADE not reported
Proportion 0.807 [0.482, 0.949]
5 studies
GRADE not reported
Proportion 0.909 [0.785, 0.965]
12 studies
GRADE not reported
Dental caries susceptibility · Ethnicity: Caucasian (n=2) individuals with caries/high caries and controls
The pooled odds ratio was 1.63 (95% CI 0.67 to 4.01).
1 finding from 1 review
OR 1.63 [0.67, 4.01]
2 studies
GRADE not reported
Dental erosion · Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR)
Reflux (GERD/LPR) is associated with a higher prevalence and severity of dental erosion than in healthy individuals, but the evidence is heterogeneous, not pooled, and ungraded.
1 finding from 1 review
Intervention not reported
Incidence of microleakage: Er,Cr:YSGG vs traditional bur (whole marginal line)
1 finding from 1 review
Qualitative NR [NR, NR]
1 study
GRADE not reported
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between AG genotype vs AA genotype of ENAM rs1264848 and dental caries susceptibility (AG vs AA model: OR 1.21, 95% CI 0.88-1.65); certainty not graded.
6 findings from 1 review
Show 3 more findings
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC genotype of AMELX rs6639060 and dental caries susceptibility (TT vs CC model: OR 1.04, 95% CI 0.43-2.51) in the Age group: Adults subgroup; certainty not graded.
3 findings from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between CT genotype vs CC genotype of AMELX rs946252 and dental caries susceptibility (CT vs CC model: OR 2.80, 95% CI 0.93-8.43) in the Ethnicity: Caucasian subgroup; certainty not graded.
6 findings from 1 review
Show 3 more findings
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between GG genotype vs AA + AG genotype of LTF rs1126478 and dental caries susceptibility (GG vs AA + AG model: OR 0.95, 95% CI 0.80-1.13) in the Age group: Children subgroup; certainty not graded.
5 findings from 1 review
Show 2 more findings
Dental caries susceptibility · Age group: Children (n=4) individuals with caries/high caries and controls
The pooled odds ratio was 0.98 (95% CI 0.87 to 1.10).
1 finding from 1 review
OR 0.98 [0.87, 1.10]
4 studies
GRADE not reported
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
The CT genotype of AMELX rs17878486 was associated with increased dental caries risk (CT vs CC model: OR 5.11, 95% CI 1.33-19.72) in the Ethnicity: Mixed subgroup; certainty not graded.
9 findings from 1 review
Show 6 more findings
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between GG genotype vs AA + AG genotype of ENAM rs3796704 and dental caries susceptibility (GG vs AA + AG model: OR 1.05, 95% CI 0.66-1.68) in the Control group: Low caries subgroup; certainty not graded.
6 findings from 1 review
Show 3 more findings
Safety of sealants and fluoride varnishes (adverse events) · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review
Intervention not reported
Absence of recurrent caries success rate
1 finding from 1 review
Dental caries susceptibility · Ethnicity: Caucasian (n=2) individuals with caries/high caries and controls
The pooled odds ratio was 0.95 (95% CI 0.35 to 2.55).
1 finding from 1 review
OR 0.95 [0.35, 2.55]
2 studies
GRADE not reported
Intervention not reported
Absence of recurrent caries success rate
1 finding from 1 review