Question · asked by 1 review

Gastroesophageal or laryngopharyngeal reflux (GERD/LPR) vs Healthy individuals without reflux (controls): Dental erosion

Reflux (GERD/LPR) is associated with a higher prevalence and severity of dental erosion than in healthy individuals, but the evidence is heterogeneous, not pooled, and ungraded.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Gastroesophageal or laryngopharyngeal reflux (GERD/LPR) vs Healthy individuals without reflux (controls)
Dental erosion (prevalence and severity) · Adults with gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR) · Adult patients in gastroenterology, ENT and dental clinical settings
Reflux (GERD/LPR) is associated with a higher prevalence and severity of dental erosion than in healthy individuals, but the evidence is heterogeneous, not pooled, and ungraded.
Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. (2020) All outcomes
Controlled studies showed GERD patients have a significantly higher rate or severity of dental erosion than healthy individuals; prevalence of dental erosion in reflux patients ranged from 16% to 44% versus <20% in…18 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review.
2020 All outcomes
January 1990 to December 2019 (publication period searched)24Not applicable

Studies behind the findings

The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.