Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Disability caused by pain at follow-up · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in disability caused by pain at treatment completion compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
2 findings from 1 review
Success rate (radiographically‐assessed healing of cyst healing based on the Neer/Cole rating system) · Adults (>18 years) with established dry socket following permanent tooth extraction
1 finding from 1 review
Healing of MRONJ (mucosal integrity, absence of infection, and no re-intervention) · People with established (manifest) MRONJ
It is very uncertain whether platelet-rich fibrin after bone surgery changes healing of MRONJ (mucosal integrity, absence of infection, and no… compared with bone surgery alone (very low certainty).
1 finding from 1 review
Pain · Adults (>18 years) with established dry socket following permanent tooth extraction
1 finding from 1 review
Duration of treatment (days) · Adults (>18 years) with established dry socket following permanent tooth extraction
Metronidazole (intrasocket) led to lower duration of treatment (days) compared with placebo; GRADE not reported.
1 finding from 1 review
Complications and side effects · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)
1 finding from 1 review
Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ compared with conventional bone surgery (very low certainty).
1 finding from 1 review
Intervention not reported
Caries experience - % with caries (descriptive), primary dentition
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Povidone iodine 1% led to lower presence of dry socket compared with control; GRADE not reported.
1 finding from 1 review
Pain (VAS cm) · Adults (>18 years) with established dry socket following permanent tooth extraction
Plasma rich in growth factors (PRGF) showed no clear difference in pain (VAS cm) compared with alvogyl; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Recombinant bovine fibroblast growth factor gel led to lower presence of dry socket compared with control; GRADE not reported.
1 finding from 1 review
Time to initial pain relief (minutes) · Adults (>18 years) with established dry socket following permanent tooth extraction
Neocone led to lower time to initial pain relief (minutes) compared with zinc oxide eugenol; GRADE not reported.
1 finding from 1 review
Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) may leads to lower pain intensity at follow-up (12 months) compared with usual care, waiting list or no treatment (control) (low certainty).
2 findings from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Platelet rich fibrin showed no clear difference in presence of dry socket compared with control; GRADE not reported.
1 finding from 1 review
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
3 trials reported no adverse events. 1 study reported adverse events (alterations in taste, bad taste, staining) in 24/62 in chlorhexidine group versus 0/40 in placebo group, Peto OR = 8.42 (95% CI 3.31 to 21.39). A…
6 studies
GRADE not reported
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Hypnosis showed no clear difference in pain intensity compared with relaxation; GRADE not reported.
1 finding from 1 review
Not pooled (clinical heterogeneity). Abrahamsen 2011: MD -1.00 (95% CI -2.27 to 0.27), n=38 (hypnosis 19, relaxation 19); Stam 1984: MD not reported, n=27 (hypnosis 12, relaxation 15).
2 studies · 65 participants
GRADE not reported
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Habit reversal treatment led to lower pain intensity compared with waiting-list control; GRADE not reported.
1 finding from 1 review