Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,252 questions · 2,353 findings · 210 reviews · Neonatal

No studies found 432 · 18.4%GRADE not reported 99 · 4.2%Very low 609 · 25.9%Low 737 · 31.3%Moderate 385 · 16.4%High 91 · 3.9%

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Sepsis without a source · newborn infants with central venous catheters

Chlorhexidine dressing following alcohol cleansing showed no clear difference in sepsis without a source compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

1 finding from 1 review

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Catheter‐related blood stream infection · newborn infants with central venous catheters

Chlorhexidine dressing following alcohol cleansing showed no clear difference in catheter‐related blood stream infection compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

1 finding from 1 review

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Catheter colonisation · newborn infants with central venous catheters

Chlorhexidine dressing following alcohol cleansing probably leads to lower catheter colonisation compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

1 finding from 1 review

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Adverse effects: contact dermatitis · newborn infants with central venous catheters

Chlorhexidine dressing following alcohol cleansing probably leads to higher adverse effects: contact dermatitis compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

1 finding from 1 review

Silver‐alginate dressing vs control

CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods · newborn infants with central venous catheters

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods compared with control (moderate certainty).

1 finding from 1 review

Silver‐alginate dressing vs control

CRBSI ‐ Unit of analysis: catheters Clinial and microbiological methods · newborn infants with central venous catheters

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: catheters Clinial and microbiological… compared with control (moderate certainty).

1 finding from 1 review