Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Musculoskeletal

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Withdrawals due to adverse events · Patients with ankylosing spondylitis

Sulfasalazine probably leads to higher total number of withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Sulfasalazine for ankylosing spondylitis 2014 · Cochrane Headline outcomes only
RR 1.43 [1.04, 1.94]
11 studies · 895 participants
Moderate

Total number of adverse events (withdrawals due to lack of effect)c · patients with varus medial osteoarthritis of the knee

1 finding from 1 review

Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 117 participants
Low

Total number of adverse events (withdrawals due to lack of effect)c · patients with varus medial osteoarthritis of the knee

The intervention showed no clear difference in total number of adverse events (withdrawals due to lack of effect)c (low certainty).

1 finding from 1 review

Braces and orthoses for treating osteoarthritis of the knee 2015 · Cochrane Headline outcomes only
RR 1.63 [0.94, 2.82]
1 study · 117 participants
Low