Question · asked by 1 review

Sulfasalazine vs placebo: Withdrawals due to adverse events

Sulfasalazine probably leads to higher total number of withdrawals due to adverse events compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Sulfasalazine vs placebo
Total number of withdrawals due to adverse events · Patients with ankylosing spondylitis
Sulfasalazine probably leads to higher total number of withdrawals due to adverse events compared with placebo (moderate certainty).
Sulfasalazine for ankylosing spondylitis (2014) · Cochrane Headline outcomes only
RR 1.43 [1.04, 1.94]11 studies · 895 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Sulfasalazine for ankylosing spondylitis
2014 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.