Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · ENT

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

Clotrimazole (partially absorbed from GI tract) vs another azole

Significant adverse events · patients with otomycosis

1 finding from 1 review

Topical azole treatments for otomycosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 174 participants
Very low

Tranexamic acid vs placebo (saline solution or sterile water)

Significant adverse events (seizures, thromboembolism) within 24 hours of surgery) · adults and children with chronic rhinosinusitis with or without nasal polyps

Tranexamic acid showed no clear difference in significant adverse events (seizures, thromboembolism) within 24… compared with placebo (saline solution or sterile water) (moderate certainty).

1 finding from 1 review

Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
RD 0
8 studies · 664 participants
Moderate