Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 20 findings · 6 reviews · Headline outcomes only

No studies found 9 · 45%GRADE not reported 0 · 0%Very low 1 · 5%Low 8 · 40%Moderate 2 · 10%High 0 · 0%

Balloon (Foley or ATAD) vs low‐dose vaginal misoprostol

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

It is very uncertain whether balloon (Foley or ATAD) changes serious neonatal morbidity or perinatal death compared with low‐dose vaginal misoprostol (very low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose oral misoprostol

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in serious neonatal morbidity or perinatal death compared with low‐dose oral misoprostol (low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs vaginal prostaglandin E2

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) probably leads to lower serious neonatal morbidity or perinatal death compared with vaginal prostaglandin E2 (moderate certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious neonatal morbidity or perinatal death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious neonatal morbidity/perinatal death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

(7.1) PGE2 (controlled release) vs all PGE2 delivery systems (all women)

Serious neonatal morbidity or perinatal death · patients with induction of labour at term

(7.1) PGE2 (controlled release) showed no clear difference in serious neonatal morbidity or perinatal death compared with all PGE2 delivery systems (all women) (low certainty).

1 finding from 1 review

Amniotic membranes sweeping vs vaginal/intracervical prostaglandins

Neonatal death or serious neonatal perinatal morbidity · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).

Amniotic membranes sweeping showed no clear difference in neonatal death or serious neonatal perinatal morbidity compared with vaginal/intracervical prostaglandins (low certainty).

1 finding from 1 review

One frequency of amniotic membranes sweeping vs another frequency of amniotic membrane sweeping

Neonatal death or serious neonatal perinatal morbidity · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).

One frequency of amniotic membranes sweeping showed no clear difference in neonatal death or serious neonatal perinatal morbidity compared with another frequency of amniotic membrane sweeping (low certainty).

1 finding from 1 review

Amniotic membranes sweeping vs no treatment/sham

Neonatal death or serious neonatal perinatal morbidity · pregnant women carrying a live fetus at or near term (≥ 36 weeks' gestation).

Amniotic membranes sweeping showed no clear difference in neonatal death or serious neonatal perinatal morbidity compared with no treatment/sham (low certainty).

1 finding from 1 review