Findings

What do systematic reviews say?

3,241 questions · 3,336 findings · 1,340 reviews

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No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

COMPARISON 1. ARIPIPRAZOLE vs CLOZAPINE

QoL · patients with schizophrenia

1 finding from 1 review

Aripiprazole versus other atypical antipsychotics for schizophrenia 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 132 participants
Very low

Intervention not reported

Mean change from baseline in quality of life score (NEI VFQ‐25 instrument) · participants with CRVO macular oedema of duration less than 9 months (mean < 3 months) and no prior treatment

1 finding from 1 review

Anti‐vascular endothelial growth factor for macular oedema secondary to central retinal vein occlusion 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 743 participants
Moderate

Summary of findings table ‐ Bladder training vs no treatment

Symptom‐ and condition‐related quality of life: immediately after treatment · overactive bladder

1 finding from 1 review

Bladder training for treating overactive bladder in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Summary of findings table ‐ Bladder training vs anticholinergics

Symptom‐ and condition‐related quality of life: immediately after treatment · overactive bladder

1 finding from 1 review

Bladder training for treating overactive bladder in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 117 participants
Very low

Reslizumab subcutaneous (SC) vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · people with asthma

1 finding from 1 review

Anti‐IL‐5 therapies for asthma 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 464 participants
High

Intervention not reported

General health‐related quality of life [assessed using a variety of scales, · women with primary breast cancer

The intervention may leads to lower general health‐related quality of life [assessed using a variety of… (low certainty).

1 finding from 1 review

Specialist breast care nurses for support of women with breast cancer 2021 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1328 participants
Low

Summary of findings ‐ Niprisan® vs placebo

Quality of life measures: self reported health, absence from work or school · people with SCD

1 finding from 1 review

Phytomedicines (medicines derived from plants) for sickle cell disease 2020 · Cochrane Headline outcomes only
no estimate extracted
70 participants
Very low

Subacromial decompression vs Placebo (sham/placebo device)

Health status and quality of life · people with impingement syndrome without full‐thickness rotator cuff tears

1 finding from 1 review

Subacromial decompression surgery for rotator cuff disease 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 285 participants
High

Summary of findings: Substitutive interventions vs control

Quality of life (Visual Function Questionnaire (VFQ‐25)) After intervention · stroke survivors with visual field defects

Summary of findings: Substitutive interventions showed no clear difference in quality of life (Visual Function Questionnaire (VFQ‐25)) After… compared with control (low certainty).

1 finding from 1 review

Interventions for visual field defects in people with stroke 2019 · Cochrane Headline outcomes only
MD 8.4
1 study · 43 participants
Low

Acetyl‐L‐carnitine vs placebo

General health‐related quality of life · patients with covert or overt hepatic encephalopathy

1 finding from 1 review

Acetyl‐L‐carnitine for patients with hepatic encephalopathy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 67 participants
Very low

Intervention diet vs control diet

Health related quality of life at 12 months ‐ SIBDQ ‐ Carrageenan‐free diet · Patients with quiescent ulcerative colitis

1 finding from 1 review

Dietary interventions for induction and maintenance of remission in inflammatory bowel disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Prism spectacles vs conventional spectacles

Mean change from baseline in quality of life score (NEI VFQ‐25 instrument) · adults with low vision (people with AMD)

1 finding from 1 review

Reading aids for adults with low vision 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 153 participants
Moderate

Cannabidiol vs placebo

IBDQ at week 6 · people with active UC

1 finding from 1 review

Cannabis for the treatment of ulcerative colitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 53 participants
Moderate

Electrical stimulation vs No active treatment (control)

OAB‐related quality of life · Adults with overactive bladder (OAB)

1 finding from 1 review

Electrical stimulation with non‐implanted electrodes for overactive bladder in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 148 participants
Low

Circular external fixation with limited internal fixation (hybrid fixation) vs standard open reduction internal fixation

Quality of Life: SF‐36 scale from 0 to 100 (higher scores = better outcome) · adults with tibial plateau fracture (Schatzker types V or VI)

1 finding from 1 review

Surgical fixation methods for tibial plateau fractures 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 66 participants
Very low

Hypertonic saline vs Normal saline

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · people with bronchiectasis

1 finding from 1 review

Inhaled hyperosmolar agents for bronchiectasis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Moderate

Quality of life measured on multiple scales (0 to 100; higher score = better quality of life) Postintervention: first assessment after end of treatment; no later than 3 months · patients with osteoarthritis

1 finding from 1 review

Self‐management education programmes for osteoarthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
226 participants
Moderate

Summary of findings: colistimethate dry powder for inhalation (Colobreathe®) vs tobramycin

QoL · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 374 participants
Low

One type of traditional sling operation vs another traditional suburethral sling

Incontinence‐specific quality of life · women with urinary incontinence

1 finding from 1 review

Traditional suburethral sling operations for urinary incontinence in women 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 282 participants
Very low

Avatar Therapy vs treatment

QoL · schizophrenia or related disorders

1 finding from 1 review

Avatar Therapy for people with schizophrenia or related disorders 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low