Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,241 questions · 3,336 findings · 1,340 reviews

No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

Intervention not reported

Health‐Related Quality of Life at least 20% improvement · patients with rheumatoid arthritis

The intervention showed no clear difference in health‐Related Quality of Life at least 20% improvement (moderate certainty).

1 finding from 1 review

Serenoa repens vs placebo or no intervention

QoL · men with lower urinary tract symptoms secondary to benign prostatic obstruction

Serenoa repens showed no clear difference in quality of lifeMeasured by IPSS‐QoL score (range 0 to 6) compared with placebo or no intervention (high certainty).

1 finding from 1 review

Dornase alfa vs placebo or no dornase alfa treatment

Quality of life: CFQ‐R respiratory domain: absolute change from baseline · adults and children with cystic fibrosis

Dornase alfa showed no clear difference in change in quality of life ‐ CFQ‐R respiratory at 1 month compared with placebo or no dornase alfa treatment (low certainty).

2 findings from 1 review

Intervention not reported

Quality of life (SF‐36, Functional Component) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Rheum officinale vs captopril

Full time working capacity Unclear quality of life scale · people with chronic kidney disease (predialysis (GFR 15 to 60 mL/min/1.73 m²), HD, PD, transplant recipients)

Rheum officinale showed no clear difference in full time working capacity Unclear quality of life scale compared with captopril (low certainty).

1 finding from 1 review

Rheum officinale vs captopril

Part‐time working capacity Unclear quality of life scale · people with chronic kidney disease (predialysis (GFR 15 to 60 mL/min/1.73 m²), HD, PD, transplant recipients)

Rheum officinale showed no clear difference in part‐time working capacity Unclear quality of life scale compared with captopril (low certainty).

1 finding from 1 review

Surgery vs Pharmacological therapy

Health‐related quality of life Mean AcroQoL score (0‐100) · adults with growth‐hormone secreting pituitary adenomas

Surgery alone showed no clear difference in health‐related quality of life Mean AcroQoL score (0‐100) compared with pharmacological therapy alone (low certainty).

1 finding from 1 review