Findings

What do systematic reviews say?

3,241 questions · 3,336 findings · 1,340 reviews

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No studies found 1,581 · 47.4%GRADE not reported 352 · 10.6%Very low 512 · 15.3%Low 509 · 15.3%Moderate 316 · 9.5%High 66 · 2%

Summary of findings for exercise plus education vs control

Quality of life immediately after the intervention · people with Parkinson's disease

1 finding from 1 review

Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 305 participants
Very low

Exercise vs control

Quality of life immediately after the intervention · people with Parkinson's disease

1 finding from 1 review

Interventions for preventing falls in Parkinson's disease 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 951 participants
Low

Recombinant human C1 esterase inhibitor vs placebo or active control

Differences in quality of life ( · children or adults with Types I or II HAE

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lay health worker‐led psychosocial interventions vs enhanced usual care

Quality of life (1 to 6 months post intervention)Â · women with perinatal depression

The review found no eligible studies for this question.

1 finding from 1 review

Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

NSAIDs vs glucocorticoids

HRQOL ‐ not measured · acute gout

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for acute gout 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Maintenance treatment with antipsychotic drugs vs placebo/no treatment

QoL · schizophrenia

1 finding from 1 review

Maintenance treatment with antipsychotic drugs for schizophrenia 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1573 participants
Low

Helium thermal coagulator vs electrodiathermy

Quality of life (9 months) – EHP‐30 social support · endometriosis

1 finding from 1 review

Laparoscopic surgery for endometriosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 119 participants
Very low

CBT vs other experimental control

Health‐related quality of life at end of treatment · adults with tinnitus

1 finding from 1 review

Cognitive behavioural therapy for tinnitus 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 95 participants
Very low

Pazopanib vs sunitinib (targeted agent versus targeted agent)

Health‐related quality of life (mean change value) · Treatment‐naïve metastatic renal cell carcinoma (clear cell type)

1 finding from 1 review

Targeted therapy for metastatic renal cell carcinoma 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 467 participants
Low

Antipsychotic dose increase vs switching the antipsychotic drug

Average change in quality of life/satisfaction · non response in schizophrenia

1 finding from 1 review

Increasing antipsychotic dose versus switching antipsychotic for non response in schizophrenia 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · patients with refractory medial temporal lobe epilepsy

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 3 participants
Very low

Intervention not reported

Quality of life ‐ physical composite SGRQ and SF36 · people with COPD

1 finding from 1 review

Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 289 participants
Low

Summary of findings table ‐ Daratumumab plus standard therapy vs usual care

Health‐related quality of life European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ‐C30). Scale from: 0 to 100 (a higher score means a better outcome) · people with newly diagnosed multiple myeloma ineligible for transplant

1 finding from 1 review

Daratumumab and antineoplastic therapy versus antineoplastic therapy only for adults with newly diagnosed multiple… 2024 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1096 participants
Low

Exercise therapy vs antidepressants

QoL · men and women aged over 18 years with chronic fatigue syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Exercise therapy for chronic fatigue syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Secondary outcome: quality of life · adults with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Loratadine 10 mg vs placebo (4‐week intervention)

Secondary outcome: quality of life · adults with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Loratadine 10 mg vs placebo (2‐week intervention)

Secondary outcome: quality of life · adults with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cetirizine 0.5 mg/kg/d vs placebo (18‐month intervention)

Secondary outcome: quality of life · children with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cetirizine 10 mg/d vs placebo (4‐week intervention)

Secondary outcome: quality of life · adults with eczema

The review found no eligible studies for this question.

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cannabis oil (15% cannabidiol and 4% THC) vs placebo oil

Quality of life Short‐Form 36 health survey (SF‐36) · Patients with active Crohn's disease

1 finding from 1 review

Cannabis for the treatment of Crohn's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low