What do systematic reviews say?

Exercise vs usual care

• Exercise therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 123 participants
  Very low

Motivational interviewing vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

SKILLS TRAINING vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

COGNITIVE BEHAVIOUR THERAPY and PSYCHOSOCIAL REHABILITATION vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Cognitive behavioural therapy + intensive case management vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention showed no clear difference in health‐related quality of life: up to 3 months ( (low certainty).

• Glucocorticosteroids for people with alcoholic hepatitis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 377 participants
  Low

Summary of findings: bevacizumab vs ranibizumab

Summary of findings: bevacizumab showed no clear difference in no problems in quality of life domains at 1 year compared with ranibizumab (moderate certainty).

• Anti‐vascular endothelial growth factor for neovascular age‐related macular degeneration 2019 · Cochrane Headline outcomes only
  RR 0.96 [0.9, 1.04]
  1 study · 548 participants
  Moderate

Short‐stay unit hospitalisation vs usual care

• Hospitalisation in short‐stay units for adults with internal medicine diseases and conditions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1029 participants
  Very low

Any antiglucocorticoid vs placebo

• Antiglucocorticoid and related treatments for psychosis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported
• Antiglucocorticoid and related treatments for psychosis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported
• Antiglucocorticoid and related treatments for psychosis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Home telemonitoring and remote feedback between clinic visits for asthma 2016 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 796 participants
  Low

Intervention not reported

• Exercise interventions on health‐related quality of life for cancer survivors 2012 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 115 participants
  Moderate

Personally tailored activities vs usual care or non‐personalised activities

• Personally tailored activities for improving psychosocial outcomes for people with dementia in long‐term care 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

Higher vs lower FiO2 or targets of arterial oxygenation

• Higher versus lower fractions of inspired oxygen or targets of arterial oxygenation for adults admitted to the… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1649 participants
  Very low

Steroids vs lubricants

The review found no eligible studies for this question.

• Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Steroids vs cyclosporine A

The review found no eligible studies for this question.

• Topical corticosteroids for dry eye 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Primary health professional‐ and community professional‐led interventions vs enhanced usual care

Primary health professional‐ and community professional‐led… showed no clear difference in quality of life (1 to 6 months post intervention) compared with enhanced usual care (moderate certainty).

• Primary‐level worker interventions for the care of people living with mental disorders and distress in low‐ and… 2021 · Cochrane Headline outcomes only
  MD 0
  1 study · 560 participants
  Moderate

Low income vs High family income

Children from low-income families had higher odds of poor OHRQoL (OR 1.16, 95% CI 1.11-1.21; 4 studies; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income country (Brazil); studies 2010-2014
  OR 1.16 [1.11, 1.21]
  4 studies
  GRADE not reported

Younger children's age (3-5 years) vs Older children (>5 years)

Children aged 3 years had higher odds of poor OHRQoL than older children (OR 2.00, 95% CI 1.42-2.57; 2 studies; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries (Brazil); studies 2011-2012 · Age 3 years
  OR 2.00 [1.42, 2.57]
  2 studies
  GRADE not reported
• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries (Brazil); studies 2011-2012 · Age 4 years
  OR 2.13 [1.50, 2.76]
  2 studies
  GRADE not reported

All exposure-OHRQoL estimates pooled for publication-bias correction (meta-trim sensitivity); specific exposure set not defined in source vs Not specified

A trim-and-fill sensitivity analysis pooling every exposure estimate gave an overall OR of 0.17 (95% CI 0.13-0.21) after correcting for significant publication bias (Fig. 13); this combined estimate spans heterogeneous exposures and is a publication-bias sensitivity result (ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Children across multiple countries (Brazil, Hong Kong, Sri Lanka, New Zealand) · Trim-and-fill adjusted (publication-bias corrected), random-effects
  OR 0.17 [0.13, 0.21]
  Studies not reported
  GRADE not reported

Periodontal disease (present) vs Individuals without periodontal disease (by LOA)

Periodontal disease was associated with higher odds of poor OHRQoL (OR 1.15, 95% CI 1.12-1.18; 3 studies; no heterogeneity; ungraded).

• The Association of Oral Health Status, demographic characteristics and socioeconomic determinants with Oral… 2020 All outcomes

  Upper-middle-income countries (Brazil); studies 2010-2014
  OR 1.15 [1.12, 1.18]
  3 studies
  GRADE not reported