Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

60 questions · 69 findings · 26 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 12 · 17.4%GRADE not reported 0 · 0%Very low 15 · 21.7%Low 16 · 23.2%Moderate 17 · 24.6%High 9 · 13%

Neuronavigation image‐guided surgery vs surgery

Progression‐free survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

iMRI image‐guided surgery vs surgery

Progression‐free survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

5‐ALA image‐guided surgery vs surgery

Progression‐free survival · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Ultra‐radical (extensive) surgery vs surgery

Progression‐free survival · women with stage IIIc or IV ovarian cancer

It is very uncertain whether ultra‐radical (extensive) surgery changes progression‐free survival compared with standard surgery (very low certainty).

1 finding from 1 review

EGFR tyrosine kinase inhibitor (TKI) vs observation

Progression‐free survival · maintenance treatment of epithelial ovarian cancer after first‐line chemotherapy

It is very uncertain whether EGFR tyrosine kinase inhibitor (TKI) changes progression‐free survival compared with observation alone (very low certainty).

1 finding from 1 review

EGFR tyrosine kinase inhibitor (TKI) plus chemotherapy vs chemotherapy alone

Progression‐free survival · treatment of relapsed epithelial ovarian cancer

It is very uncertain whether EGFR tyrosine kinase inhibitor (TKI) plus chemotherapy changes progression‐free survival compared with chemotherapy alone (very low certainty).

1 finding from 1 review

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery plus WBRT

Progression‐free survival · people with single or solitary brain metastasis

Surgery plus whole brain radiotherapy (WBRT) showed no clear difference in progression‐free survival compared with stereotactic radiosurgery plus WBRT (low certainty).

1 finding from 1 review