Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 13 findings · 6 reviews · Stroke

No studies found 1 · 7.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 7.7%Moderate 4 · 30.8%High 7 · 53.8%

Dual vs one antiplatelet agent

Stroke, myocardial infarction, or vascular death · preventing early recurrence after ischaemic stroke or TIA

Dual probably leads to lower stroke, myocardial infarction, or vascular death compared with one antiplatelet agent (moderate certainty).

1 finding from 1 review

Multiple vs fewer antiplatelet agents

Stroke, myocardial infarction, or vascular death · preventing early recurrence after ischaemic stroke or TIA

Multiple probably leads to lower stroke, myocardial infarction, or vascular death compared with fewer antiplatelet agents (moderate certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke or myocardial infarction between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke or myocardial infarction between randomisation… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke or myocardial infarction between randomisation and 30 days after treatment · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or any stroke or myocardial infarction between randomisation… compared with endarterectomy (moderate certainty).

1 finding from 1 review

Blood pressure‐lowering drugs (BPLDs) vs placebo or no treatment

Stroke, myocardial infarction, or vascular death · stroke and/or TIA

Blood pressure‐lowering drugs (BPLDs) showed no clear difference in major vascular event (composite of non‐fatal stroke, non‐fatal… compared with placebo or no treatment (high certainty).

1 finding from 1 review