Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

251 questions · 251 findings · 100 reviews · Hepato-Biliary

No studies found 36 · 14.3%GRADE not reported 13 · 5.2%Very low 160 · 63.7%Low 30 · 12%Moderate 10 · 4%High 2 · 0.8%

L‐ornithine L‐aspartate vs probiotic

All‐cause mortality · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes mortality compared with probiotic (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs rifaximin

All‐cause mortality · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes mortality compared with rifaximin (very low certainty).

1 finding from 1 review

L‐ornithine L‐aspartate vs lactulose

All‐cause mortality · people with cirrhosis who had minimal or overt hepatic encephalopathy or who were at risk for developing hepatic encephalopathy;…

It is very uncertain whether L‐ornithine L‐aspartate changes mortality compared with lactulose (very low certainty).

1 finding from 1 review