Intervention not reported
Minor adverse events · [People] with [Multiple Sclerosis]
1 finding from 1 review
- no estimate extracted8 studies · 701 participantsLow
Findings
What do systematic reviews say?
83 questions · 83 findings · 29 reviews
No studies found 25 · 30.1%GRADE not reported 2 · 2.4%Very low 21 · 25.3%Low 20 · 24.1%Moderate 13 · 15.7%High 2 · 2.4%
Desmopressin vs placebo
Minor adverse events
Desmopressin showed no clear difference in minor adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 0.86 [0.49, 1.49]1 study · 115 participantsLow
Desmopressin vs alpha‐blocker
Minor adverse events
It is very uncertain whether desmopressin changes minor adverse events compared with alpha‐blocker (very low certainty).
1 finding from 1 review
- RR 1.07 [0.07, 15.57]1 study · 31 participantsVery low
Desmopressin plus alpha‐blocker vs alpha‐blocker
Minor adverse events
It is very uncertain whether desmopressin plus alpha‐blocker changes minor adverse events compared with alpha‐blocker (very low certainty).
1 finding from 1 review
- RR 1.6 [0.15, 16.82]3 studies · 402 participantsVery low
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Minor adverse events
Desmopressin plus alpha‐blocker may leads to lower minor adverse events compared with alpha‐blocker plus anticholinergic (low certainty).
1 finding from 1 review
- RR 0.22 [0.05, 0.98]1 study · 427 participantsLow
Macrolides vs other antibiotics
Minor adverse events · sexually active adults
It is very uncertain whether macrolides changes minor adverse events compared with any other antibiotic (very low certainty).
1 finding from 1 review
- Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults 2017 · Cochrane Headline outcomes onlyRR 1.34 [0.24, 7.51]3 studies · 412 participantsVery low
Erythromycin vs any other macrolide
Minor adverse events · sexually active adults
It is very uncertain whether macrolide (erythromycin) changes minor adverse events compared with any other macrolide (very low certainty).
1 finding from 1 review
- Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults 2017 · Cochrane Headline outcomes onlyRR 1.14 [0.63, 2.06]1 study · 101 participantsVery low
Oral hydroxychloroquine vs placebo
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
Oral hydroxychloroquine showed no clear difference in adverse events: minor compared with placebo (moderate certainty).
1 finding from 1 review
- Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes onlyRR 1.32 [0.24, 7.19]1 study · 47 participantsModerate
Oral dehydroepiandrosterone vs placebo
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
Oral dehydroepiandrosterone probably leads to higher adverse events: minor compared with placebo (moderate certainty).
1 finding from 1 review
- Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes onlyRR 10.5 [3.26, 33.75]1 study · 381 participantsModerate
Oral chloroquine vs placebo
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
1 finding from 1 review
- Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes onlyno estimate extracted0 studies · 0 participantsGRADE not reported
Oral methotrexate vs oral chloroquine
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
Oral methotrexate may leads to higher adverse events: minor compared with oral chloroquine (low certainty).
1 finding from 1 review
- Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes onlyRR 3.9 [1.45, 10.51]1 study · 41 participantsLow
Oral methotrexate vs placebo
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
Oral methotrexate showed no clear difference in adverse events: minor compared with placebo (moderate certainty).
1 finding from 1 review
- Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes onlyRR 0.68 [0.39, 1.17]1 study · 86 participantsModerate
Oral contraceptive pill (OCP) vs metformin combined with OCP
Minor adverse events · aAdult women with PCOS
Oral contraceptive pill (OCP) may leads to lower adverse events ‐ Minor compared with metformin combined with OCP (low certainty).
1 finding from 1 review
- Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary… 2020 · Cochrane Headline outcomes onlyOR 0.06 [0.01, 0.44]2 studies · 98 participantsLow
Metformin vs oral contraceptive pill (OCP)
Minor adverse events · adult women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
- Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary… 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Oral contraceptive pill (OCP) vs metformin combined with OCP
Minor adverse events · adolescent women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
- Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary… 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Metformin vs metformin combined with OCP
Minor adverse events · adult women with PCOS
The review found no eligible studies for this question.
1 finding from 1 review
- Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary… 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Acupuncture vs sham
Number of minor adverse events · Adults with overactive bladder (OAB)
Acupuncture showed no clear difference in number of minor adverse events compared with sham acupuncture (moderate certainty).
1 finding from 1 review
- RR 1.28 [0.3, 5.36]4 studies · 222 participantsModerate
Acupuncture vs medication
Number of minor adverse events · Adults with overactive bladder (OAB)
Acupuncture may leads to lower number of minor adverse events compared with medication (low certainty).
1 finding from 1 review
- RR 0.34 [0.26, 0.45]8 studies · 1004 participantsLow
Acupuncture vs no treatment
Number of minor adverse events · Adults with overactive bladder (OAB)
1 finding from 1 review
- no estimate extracted1 study · 24 participantsVery low
Anticoagulant vs different dose of the same anticoagulant
Adverse events (minor bleeding) · non‐hospitalised individuals with COVID‐19 (asymptomatic and mild disease)
Anticoagulant showed no clear difference in adverse events (minor bleeding) compared with different dose of the same anticoagulant (low certainty).
1 finding from 1 review
- Prophylactic anticoagulants for non‐hospitalised people with COVID‐19 2023 · Cochrane Headline outcomes onlyRR 0.47 [0.09, 2.54]1 study · 278 participantsLow