Findings

What do systematic reviews say?

39 questions · 39 findings · 23 reviews

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No studies found 13 · 33.3%GRADE not reported 1 · 2.6%Very low 5 · 12.8%Low 13 · 33.3%Moderate 6 · 15.4%High 1 · 2.6%

Metformin 500 mg to 2550 mg per day vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Finasteride 5 mg vs spironolactone 100 mg

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Flutamide 250 mg b.i.d. vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life (HRQOL), natural units: measured on FACT‐G (from 0 to 108) · patients with advanced cancer

1 finding from 1 review

Early palliative care for adults with advanced cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1028 participants
Low

Exercise vs no exercise

Health‐related quality of life (HRQoL) · people with Child‐Pugh stage A or B cirrhosis

1 finding from 1 review

Physical exercise for people with cirrhosis 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 81 participants
Low

Hospital‐based specialist palliative care vs usual care

Health‐related quality of life (HRQoL) · adults with advanced illness and their unpaid caregivers/families

1 finding from 1 review

The effectiveness and cost‐effectiveness of hospital‐based specialist palliative care for adults with advanced illness… 2020 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1344 participants
Low

Summary of findings table ‐ Systemic therapy vs control

Health‐related quality of life (HRQoL) · women with early breast cancer

1 finding from 1 review

Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Low

Relaxation vs usual care

Health‐related quality of life (HRQoL) · people with ESKD

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surgical vs non‐surgical treatment

Quality of Life: SF‐36 (physical component) · people aged over 14 years with displaced intra‐articular calcaneal fractures

1 finding from 1 review

Surgical versus non‐surgical interventions for displaced intra‐articular calcaneal fractures 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 192 participants
Low

Parent‐only interventions vs minimal contact control

Health‐related quality of life (HRQoL) · children with overweight or obesity

1 finding from 1 review

Parent‐only interventions for childhood overweight or obesity in children aged 5 to 11 years 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 93 participants
GRADE not reported

Information or education intervention vs no education

Health‐related quality of life (HRQoL) · adult ICU patients and their carers

1 finding from 1 review

Information or education interventions for adult intensive care unit (ICU) patients and their carers 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 143 participants
Very low

ICU follow‐up services vs standard care or no follow‐up service

Health‐related quality of life (HRQoL) · adult survivors of the ICU, excluding those already in an existing follow‐up or rehabilitation programme

1 finding from 1 review

Follow‐up services for improving long‐term outcomes in intensive care unit (ICU) survivors 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 286 participants
Low

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Intervention not reported

Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale · individuals with stable bronchiectasis

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Intervention not reported

Health‐related quality of life (HRQOL), SD units: measured on FACIT‐Pal, TOI of FACT‐Hep, TOI of FACT‐L, FACT‐G, McGill Quality of Life, FACIT‐Sp. Higher scores indicate better HRQOL. · patients with advanced cancer

1 finding from 1 review

Early palliative care for adults with advanced cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1028 participants
Low

Intervention not reported

Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire Scale from 0 to 133; higher score indicates better HRQoL. Contains 19 questions from 3 domains on a Likert scale · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

CBT vs usual care

Health‐related quality of life (HRQoL) · people with ESKD

Cognitive‐behavioural therapy probably leads to higher health‐related quality of life Investigators measured health‐related… compared with usual care (moderate certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
SMD 0.51 [0.19, 0.83]
4 studies · 230 participants
Moderate