Findings

What do systematic reviews say?

301 questions · 304 findings · 123 reviews · Headline outcomes only

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No studies found 90 · 29.6%GRADE not reported 44 · 14.5%Very low 43 · 14.1%Low 57 · 18.8%Moderate 64 · 21.1%High 6 · 2%

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Change in quality of life · treatment for asthma in adults and children with asthma and GORD

1 finding from 1 review

Pharmacological and surgical interventions for the treatment of gastro‐oesophageal reflux in adults and children with… 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1595 participants
Low

Pulmonary rehabilitation vs no pulmonary rehabilitation

Change in quality of life · idiopathic pulmonary fibrosis

1 finding from 1 review

Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 194 participants
Moderate

Pulmonary rehabilitation vs no pulmonary rehabilitation

Change in quality of life · interstitial lung disease

1 finding from 1 review

Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 478 participants
Moderate

Physical exercise training vs control

Change in quality of life · individuals with stable bronchiectasis

1 finding from 1 review

Exercise training for bronchiectasis 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 110 participants
Low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in quality of life · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low

Oral gabapentin vs placebo

Change in quality of life · adults with SMA types II and III

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 67 participants
Low

Oral hydroxyurea vs placebo

Change in quality of life · children and adults with SMA types II and III

The review found no eligible studies for this question.

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intrathecal injected nusinersen vs sham

Change in quality of life · children with SMA type II

The review found no eligible studies for this question.

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral olesoxime vs placebo

Change in quality of life · non‐ambulatory children and adolescents with SMA types II and III

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 108 participants
Low

Oral creatine vs placebo

Change in quality of life · children with SMA types II and III

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Low

Oral phenylbutyrate vs placebo

Change in quality of life · children with SMA type II

The review found no eligible studies for this question.

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Subcutaneous somatotropin vs placebo

Change in quality of life · children and adults with SMA types II and III

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
19 participants
Very low

Intravenous thyrotropin releasing hormone vs placebo

Change in quality of life · children with SMA types II and III

The review found no eligible studies for this question.

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral valproic acid plus acetyl‐L‐carnitine vs placebo

Change in quality of life · non‐ambulatory children with SMA types II and III

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 54 participants
Very low

Oral valproic acid vs placebo

Change in quality of life · ambulatory adults with SMA type III

1 finding from 1 review

Drug treatment for spinal muscular atrophy types II and III 2020 · Cochrane Headline outcomes only
no estimate extracted
28 participants
Moderate

Intervention vs usual care

Change in quality of life · postural abnormalities in people with cystic fibrosis

1 finding from 1 review

Physical therapies for postural abnormalities in people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 50 participants
Very low

Elemental formula supplements vs no supplementation

Change in quality of life · Participants with Crohn's disease in remission

The review found no eligible studies for this question.

1 finding from 1 review

Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Enteral nutrition vs 6‐MP

Change in quality of life · Participants with Crohn's disease in remission

The review found no eligible studies for this question.

1 finding from 1 review

Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Enteral nutrition vs mesalamine

Change in quality of life · Participants with Crohn's disease in remission

The review found no eligible studies for this question.

1 finding from 1 review

Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Elemental formula supplements vs polymeric formula supplements

Change in quality of life · Participants with Crohn's disease in remission

The review found no eligible studies for this question.

1 finding from 1 review

Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found