Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 20 findings · 10 reviews · Headline outcomes only

No studies found 1 · 5%GRADE not reported 0 · 0%Very low 14 · 70%Low 2 · 10%Moderate 2 · 10%High 1 · 5%

Intervention not reported

All‐cause mortality at maximum · patients without heart failure

The intervention probably leads to lower all‐cause mortality at maximum (moderate certainty).

1 finding from 1 review

Meropenem vs usual care

All‐cause mortality maximum · newborns with late‐onset sepsis

It is very uncertain whether meropenem changes all‐cause mortality maximum compared with standard care (very low certainty).

1 finding from 1 review

External beam radiotherapy (EBRT) plus transarterial chemoembolisation (TACE) vs TACE alone

Mortality Number of deaths at maximum · participants with unresectable hepatocellular carcinoma

External beam radiotherapy (EBRT) plus transarterial… may leads to lower all‐cause mortality (at maximum 1‐year compared with TACE alone (low certainty).

1 finding from 1 review