What do systematic reviews say?

Zuclopenthixol dihydrochloride vs CLOZAPINE

• Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Zuclopenthixol dihydrochloride vs haloperidol

• Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Zuclopenthixol dihydrochloride vs OTHER ANTIPSYCHOTIC: h. THIOTHIXENE

• Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Zuclopenthixol dihydrochloride vs trifluoperazine

• Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Zuclopenthixol dihydrochloride vs zuclopenthixol depot

• Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

PERPHENAZINE vs placebo

It is very uncertain whether PERPHENAZINE changes adverse events: extrapyramidal adverse effects ‐ dystonia ‐ short term compared with PLACEBO (very low certainty).

• Perphenazine for schizophrenia 2015 · Cochrane Headline outcomes only
  RR 1 [0.07, 15.08]
  1 study · 48 participants
  Very low

Gabapentin vs placebo

Gabapentin probably leads to higher adverse effects: dizzinessNumber of participants experiencing… compared with placebo (moderate certainty).

• Gabapentin add‐on treatment for drug‐resistant focal epilepsy 2021 · Cochrane Headline outcomes only
  RR 2.43
  6 studies · 1206 participants
  Moderate

Pharmacological interventions vs placebo/usual care or different forms of intervention

• Interventions for sexual dysfunction following stroke 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 114 participants
  Very low

Topical vitamin D derivative vs placebo

Topical vitamin D derivative showed no clear difference in proportion of participants with adverse effects ‐ measured over 8… compared with placebo (moderate certainty).

• Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
  RR 0.87 [0.64, 1.19]
  1 study · 188 participants
  Moderate

Puvatherapy vs placebo or no treatment

• Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 22 participants
  Very low

Triamcinolone acetonide 0.1% cream with occlusive dressing vs clobetasol cream 0.05% cream

• Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 19 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain… 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mirtazapine adjunct vs placebo adjunct

Mirtazapine adjunct may leads to lower adverse effects: extrapyramidal ‐ clinically important change… compared with placebo adjunct (low certainty).

• Mirtazapine adjunct for people with schizophrenia 2018 · Cochrane Headline outcomes only
  RR 0.33 [0.2, 0.52]
  2 studies · 86 participants
  Low

Prophylactic platelet transfusion prior to surgery vs no prophylactic platelet transfusion prior to surgery

• Prophylactic platelet transfusions prior to surgery for people with a low platelet count 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 64 participants
  Very low

Intervention not reported

• Interventions to change the behaviour of health professionals and the organisation of care to promote weight reduction… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 96 participants
  Low

Videolaryngoscopy vs direct laryngoscopy

• Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

The review found no eligible studies for this question.

• Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
  The studies did not report adverse events.
  0 studies
  No studies found

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

The review found no eligible studies for this question.

• Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
  Only root resorption was assessed; other adverse effects (gingival disease, demineralisation) were not reported.
  0 studies
  No studies found

Etretinate vs placebo or no treatment

It is very uncertain whether etretinate changes proportion of participants with adverse effects ‐ measured over 12… compared with placebo or no treatment (very low certainty).

• Interventions for chronic palmoplantar pustulosis 2020 · Cochrane Headline outcomes only
  RR 3.5 [0.95, 12.9]
  1 study · 20 participants
  Very low