NSAIDs vs combined OCP
Adverse events · women with primary dysmenorrhoea
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
55 questions · 55 findings · 19 reviews
No studies found 13 · 23.6%GRADE not reported 4 · 7.3%Very low 12 · 21.8%Low 12 · 21.8%Moderate 10 · 18.2%High 4 · 7.3%
NSAIDs vs placebo
Adverse events
It is very uncertain whether NSAIDs changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
- Paracetamol (acetaminophen) or non‐steroidal anti‐inflammatory drugs, alone or combined, for pain relief in acute… 2023 · Cochrane Headline outcomes onlyRR 1.76 [0.44, 7.1]1 study · 146 participantsVery low
NSAIDs vs paracetamol
Adverse events
It is very uncertain whether NSAIDs changes adverse events compared with paracetamol (very low certainty).
1 finding from 1 review
- Paracetamol (acetaminophen) or non‐steroidal anti‐inflammatory drugs, alone or combined, for pain relief in acute… 2023 · Cochrane Headline outcomes onlyRR 1.71 [0.43, 6.9]3 studies · 281 participantsVery low
NSAIDs vs placebo
Serious adverse events · adults with fibromyalgia
1 finding from 1 review
- Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedVery low
NSAIDs vs opioid
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
- Relief of pain due to uterine cramping/involution after birth 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
NSAIDs vs herbal analgesia
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
- Relief of pain due to uterine cramping/involution after birth 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
NSAIDs vs placebo
Neonatal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
The review found no eligible studies for this question.
1 finding from 1 review
- Relief of pain due to uterine cramping/involution after birth 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
NSAIDs vs glucocorticoids
Total adverse events · acute gout
NSAIDs probably leads to higher total adverse events compared with glucocorticoids (moderate certainty).
1 finding from 1 review
- RR 1.62 [1.03, 2.55]Studies not reportedModerate
NSAIDs vs placebo
Total adverse events · acute gout
NSAIDs showed no clear difference in total adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 0.2 [0.01, 3.85]Studies not reportedLow
NSAIDs vs opioid
Neurological adverse effects · acute soft tissue injury
NSAID probably leads to lower neurological adverse events compared with opioid (moderate certainty).
1 finding from 1 review
- Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes onlyRR 0.4 [0.3, 0.53]5 studies · 1151 participantsModerate
NSAIDs vs combination (paracetamol and opioid) analgesic
Neurological adverse effects · people with acute soft tissue injury, such as ankle sprain
It is very uncertain whether NSAID changes neurological adverse events compared with combination (paracetamol and opioid) analgesic (very low certainty).
1 finding from 1 review
- Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes onlyRR 0.52 [0.09, 2.84]3 studies · 141 participantsVery low
NSAIDs vs paracetamol
Neurological adverse effects · people with acute soft tissue injury, such as ankle sprain
NSAID showed no clear difference in neurological adverse events compared with paracetamol (low certainty).
1 finding from 1 review
- Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes onlyRR 0.85 [0.62, 1.17]9 studies · 1679 participantsLow
Oral NSAIDs vs placebo
Adverse events · Adults with lateral elbow pain
1 finding from 1 review
- Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 292 participantsGRADE not reported
Oral NSAIDs vs glucocorticoid injection
Adverse events · Adults with lateral elbow pain
The review found no eligible studies for this question.
1 finding from 1 review
- Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
NSAIDs vs opioid
Gastrointestinal adverse events · acute soft tissue injury
NSAID probably leads to lower gastrointestinal adverse events compared with opioid (moderate certainty).
1 finding from 1 review
- Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes onlyRR 0.48 [0.36, 0.62]5 studies · 1151 participantsModerate
NSAIDs vs combination (paracetamol and opioid) analgesic
Gastrointestinal adverse events · people with acute soft tissue injury, such as ankle sprain
It is very uncertain whether NSAID changes gastrointestinal adverse events compared with combination (paracetamol and opioid) analgesic (very low certainty).
1 finding from 1 review
- Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes onlyRR 0.21 [0.03, 1.74]3 studies · 141 participantsVery low
NSAIDs vs paracetamol
Gastrointestinal adverse events · people with acute soft tissue injury, such as ankle sprain
NSAID showed no clear difference in gastrointestinal adverse events compared with paracetamol (low certainty).
1 finding from 1 review
- Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury 2020 · Cochrane Headline outcomes onlyRR 1.34 [0.97, 1.86]10 studies · 1504 participantsLow
NSAIDs vs herbal analgesia
Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
It is very uncertain whether NSAID changes maternal adverse events (1 hour) compared with herbal analgesia (very low certainty).
1 finding from 1 review
- Relief of pain due to uterine cramping/involution after birth 2020 · Cochrane Headline outcomes onlyRR 5 [0.6, 41.39]1 study · 108 participantsVery low
NSAIDs vs opioid
Maternal adverse events (6 to 8 hours) · women who have given birth vaginally, requiring analgesia for after‐birth pains.
NSAID may leads to lower maternal adverse events (6 to 8 hours) compared with opioid (low certainty).
1 finding from 1 review
- Relief of pain due to uterine cramping/involution after birth 2020 · Cochrane Headline outcomes onlyRR 0.62 [0.43, 0.89]3 studies · 255 participantsLow
NSAIDs vs placebo
Maternal adverse events · women who have given birth vaginally, requiring analgesia for after‐birth pains.
NSAID showed no clear difference in maternal adverse events (4 to 8 hours) compared with placebo (low certainty).
1 finding from 1 review
- Relief of pain due to uterine cramping/involution after birth 2020 · Cochrane Headline outcomes onlyRR 1.05 [0.78, 1.41]9 studies · 598 participantsLow