Cochrane · systematic review · CD012332
Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults
Derry, S, Wiffen, PJ, Häuser, W, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
Pain, Palliative and Supportive CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
NSAID compared with placebo for fibromyalgia
Population: adults with fibromyalgia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Substantial pain relief: at least 50% reduction in pain, or PGIC much improved NSAID vs placebo | no estimate extracted | 2 studies · 146 participants | Very low |
Moderate pain relief: at least 30% reduction in pain, or PGIC much or very much improved NSAID vs placebo | no estimate extracted | 3 studies · 192 participants | Very low |
Serious adverse events NSAID vs placebo | no estimate extracted | NR | Very low |
Adverse event withdrawal NSAID vs placebo | RD 0.04 | 4 studies · 230 participants | Very low |
Participants experiencing any adverse event NSAID vs placebo | RD 0.08 | 4 studies · 230 participants | Very low |
All cause withdrawal NSAID vs placebo | RD 0.03 | 3 studies · 192 participants | Very low |
Death NSAID vs placebo | no estimate extracted | NR | Very low |