Findings

What do systematic reviews say?

479 questions · 510 findings · 52 reviews

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No studies found 99 · 19.4%GRADE not reported 64 · 12.5%Very low 144 · 28.2%Low 146 · 28.6%Moderate 57 · 11.2%High 0 · 0%

Third wave CBT vs TAU

Acceptability (number of participants lost to post‐treatment assessment) · depression

It is very uncertain whether third wave CBT changes treatment acceptability (dropout) at post‐treatment compared with TAU (very low certainty).

1 finding from 1 review

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression 2013 · Cochrane Headline outcomes only
RR 1.01 [0.08, 12.3]
4 studies · 224 participants
Very low

Third wave CBT vs TAU

Clinical non‐remission at post‐treatment · depression

It is very uncertain whether third wave CBT changes clinical non‐remission at post‐treatment compared with TAU (very low certainty).

1 finding from 1 review

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression 2013 · Cochrane Headline outcomes only
RR 0.77 [0.67, 0.88]
2 studies · 140 participants
Very low

Third wave CBT vs TAU

Depression levels at post‐treatment · depression

1 finding from 1 review

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 211 participants
Very low

Third wave CBT vs TAU

Anxiety · depression

1 finding from 1 review

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Third wave CBT vs TAU

Social adjustment levels at post‐treatment— behavioural activation vs TAU Work and Social Ajustment Scale (WSAS) · depression

1 finding from 1 review

'Third wave' cognitive and behavioural therapies versus treatment as usual for depression 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Group non‐TFCBT vs Waitlist/Usual Care

Leaving the study early · Adults with PTSD for at least 3 months

1 finding from 1 review

Psychological therapies for chronic post‐traumatic stress disorder (PTSD) in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 47 participants
Very low

CBT (plus taper) vs taper

Successful discontinuation of BZDs‐ post treatment Objective and subjective · patients with BZD harmful use, abuse or dependence

CBT (plus taper) probably leads to higher successful discontinuation of BZDs‐ post treatment Objective and… compared with taper (moderate certainty).

1 finding from 1 review

Psychosocial interventions for benzodiazepine harmful use, abuse or dependence 2015 · Cochrane Headline outcomes only
RR 1.4 [1.05, 1.86]
9 studies · 423 participants
Moderate

CBT (plus taper) vs taper

Successful discontinuation of BZDs‐ 12 month · patients with BZD harmful use, abuse or dependence

CBT (plus taper) showed no clear difference in successful discontinuation of BZDs‐ 12 month compared with taper (moderate certainty).

1 finding from 1 review

Psychosocial interventions for benzodiazepine harmful use, abuse or dependence 2015 · Cochrane Headline outcomes only
RR 1.42 [0.89, 2.28]
5 studies · 284 participants
Moderate

CBT (plus taper) vs taper

Reduce BZDs> 50% ‐ post treatment Objective · patients with BZD harmful use, abuse or dependence

CBT (plus taper) showed no clear difference in reduce BZDs> 50% ‐ post treatment Objective compared with taper (low certainty).

1 finding from 1 review

Psychosocial interventions for benzodiazepine harmful use, abuse or dependence 2015 · Cochrane Headline outcomes only
OR 0.93 [0.11, 8.18]
3 studies · 178 participants
Low

CBT (plus taper) vs taper

Reduce BZDs> 50% ‐ 12 month · patients with BZD harmful use, abuse or dependence

CBT (plus taper) showed no clear difference in reduce BZDs> 50% ‐ 12 month compared with taper (low certainty).

1 finding from 1 review

Psychosocial interventions for benzodiazepine harmful use, abuse or dependence 2015 · Cochrane Headline outcomes only
OR 1.07 [0.14, 8.21]
2 studies · 125 participants
Low

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

Severity of PTSD symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 13 participants
Low

Individual TF‐CBT vs EMDR

Severity of PTSD symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Very low

Individual TF‐CBT vs EMDR

Quality of life: 1. General quality of life · Adults with co‐morbid PTSD and SMI

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Individual TF‐CBT vs EMDR

Symptoms of co‐morbid psychosis: 1. Overall mental state · Adults with co‐morbid PTSD and SMI

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Individual TF‐CBT vs EMDR

Anxiety · Adults with co‐morbid PTSD and SMI

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Individual TF‐CBT vs EMDR

Depressive symptoms · Adults with co‐morbid PTSD and SMI

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

Quality of life: 1. General quality of life · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Individual TF‐CBT vs EMDR

Adverse events ‐ incidents of unspecified severe events ‐ medium term · Adults with co‐morbid PTSD and SMI

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Individual TF‐CBT vs EMDR

Health economics · Adults with co‐morbid PTSD and SMI

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Individual TF‐CBT vs Brief PTSD psychoeducation

Severity of PTSD symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Low