Question

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000): Bleeding: Number of days on which a significant bleeding event occurred3

Population
People with a haematological disorder
Intervention
Prophylactic platelet transfusion at threshold of 10,000
Comparison
higher transfusion threshold (20,000 or 30,000)
Outcome
Bleeding: Number of days on which a significant bleeding event occurred3

Reviews word the same question differently. Two decision models (TypeSafe's Jev and Liquid AI's d1) judged each wording of the population, intervention, comparator and outcome against the others, and rows count as this question only when both agree on all four. Timing, setting and subgroup never split a question: they are shown on each row.

Reviews
2
current versions
Answers
2
all review versions
GRADE rated
2
answers with a certainty rating
Included studies linked
0
full-text reviews only
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

How each review answered it

Current versions only
QuestionEffectEvidenceStatus / GRADE
Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)
Number of days on which clinically significant bleeding occurred per participant up to 30 days from study entry · People with a haematological disorder
Comparison of different platelet count thresholds to guide administration of prophylactic platelet… (2015) · Cochrane
no estimate extracted1 study · 255 participantsLow
Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)
Bleeding: Number of days on which clinically significant bleeding occurred5 · Patients with a haematological disorder
Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after… (2012) · Cochrane
RR 1.72 [1.33, 2.22]2 studies · 94205 participantsModerate

Trials and studies behind the answers

The primary studies that full-text reviews tie to these outcomes. Reviews from the Summary of Findings tier list no included studies here, and trials have not yet been matched to questions on their own, so this list is incomplete.

No included studies are linked to these answers yet.