Gamma‐globulin vs control (no preparation or saline preparation): Subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs
Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology… compared with control (saline or no treatment) (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Gamma‐globulin vs control (saline or no treatment) Subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology… compared with control (saline or no treatment) (moderate certainty). Post‐exposure passive immunisation for preventing rubella and congenital rubella syndrome (2015) · Cochrane Headline outcomes only | RR 0.2 [0.04, 1] | 3 studies · 28 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Post‐exposure passive immunisation for preventing rubella and congenital rubella syndrome 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.