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Evidence found and GRADE certainty

7 questions · 7 findings · 1 reviews

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No studies found 3 · 42.9%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 2 · 28.6%High 1 · 14.3%

Gamma‐globulin vs control (no preparation or saline preparation)

Rubella cases Initial meta‐analysis ‐ clinical diagnosis or serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella

Gamma‐globulin probably leads to lower rubella cases Initial meta‐analysis ‐ clinical diagnosis or serology… compared with control (saline or no treatment) (moderate certainty).

1 finding from 1 review

Gamma‐globulin vs control (no preparation or saline preparation)

Subgroup: rubella cases Estimated dose 0.027 to 0.037 ml/lb11 Clinical diagnosis by 2 physicians · susceptible people exposed to rubella

Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.027 to 0.037 ml/lb11… compared with control (saline or no treatment) (low certainty).

1 finding from 1 review

Gamma‐globulin vs control (no preparation or saline preparation)

Subgroup: rubella cases Estimated dose 0.1 to 0.15 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella

Gamma‐globulin leads to lower subgroup: rubella cases Estimated dose 0.1 to 0.15 ml/lb11 Serology… compared with control (saline or no treatment) (high certainty).

1 finding from 1 review

Gamma‐globulin vs control (no preparation or saline preparation)

Subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology +/‐ virus isolation +/‐ clinical signs · susceptible people exposed to rubella

Gamma‐globulin showed no clear difference in subgroup: rubella cases Estimated dose 0.2 to 0.5 ml/lb11 Serology… compared with control (saline or no treatment) (moderate certainty).

1 finding from 1 review