Question · asked by 1 review
0-19 remaining teeth vs 20-32 remaining teeth: Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality)
In prospective cohorts, the crude HR for ACVD-related events in adults with 0-19 teeth vs adults with 20-32 teeth was 2.27 (95% CI 1.50 to 3.43; 1 study, I2 not applicable (single study)); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
0-19 remaining teeth vs 20-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Crude In prospective cohorts, the crude HR for ACVD-related events in adults with 0-19 teeth vs adults with 20-32 teeth was 2.27 (95% CI 1.50 to 3.43; 1 study, I2 not applicable (single study)); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources). Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) All outcomes | HR 2.27 [1.50, 3.43] | 1 study · 4380 participants | GRADE not reported |
0-19 remaining teeth vs 20-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Adjusted for age/sex In prospective cohorts, the age/sex-adjusted HR for ACVD-related events in adults with 0-19 teeth vs adults with 20-32 teeth was 1.29 (95% CI 1.08 to 1.53; 3 studies, I2=58%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources). Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) All outcomes | HR 1.29 [1.08, 1.53] | 3 studies · 186749 participants | GRADE not reported |
0-19 remaining teeth vs 20-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report In prospective cohorts, adults with 0-19 teeth had a higher cumulative incidence of ACVD-related events than adults with 20-32 teeth (RR 1.98, 95% CI 1.86 to 2.10; 4 cohort studies, I2=0%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources). Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) All outcomes | RR 1.98 [1.86, 2.10] | 4 studies · 191129 participants | Moderate |
0-19 remaining teeth vs 20-32 remaining teeth Atherosclerotic cardiovascular disease (ACVD)-related events (morbidity and mortality) · Adults (any age) with a known number of remaining teeth, followed prospectively in cohort studies · Community-based and clinical cohorts worldwide (all continents); events ascertained from medical records, death certificates/registers, or self-report, Multivariable-adjusted In prospective cohorts, the multivariable-adjusted HR for ACVD-related events in adults with 0-19 teeth vs adults with 20-32 teeth was 1.19 (95% CI 1.13 to 1.26; 4 studies, I2=0%); GRADE per-analysis ratings reported in Supplementary File 7 (not available in provided sources). Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of… (2021) All outcomes | HR 1.19 [1.13, 1.26] | 4 studies · 191129 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Lower Number of Teeth Is Related to Higher Risks for ACVD and Death-Systematic Review and Meta-Analyses of Survival Data. 2021 All outcomes | Before 17 June 2020 | 140 | Not applicable |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.