Anticonvulsant vs placebo: Number of participants using cocaine during the treatment (as days/week by urine tests or self report) Number of participants that reported the use of cocaine during the treatment
Any anticonvulsant showed no clear difference in use of cocaine (self reported or objective) Number of participants… compared with placebo (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Any anticonvulsant vs placebo Use of cocaine (self reported or objective) Number of participants who reported the use of cocaine during treatment, and/or number of participants with urine samples positive for cocaine · patients with cocaine dependence Any anticonvulsant showed no clear difference in use of cocaine (self reported or objective) Number of participants… compared with placebo (moderate certainty). Anticonvulsants for cocaine dependence (2015) · Cochrane Headline outcomes only | RR 0.92 [0.84, 1.02] | 9 studies · 867 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Anticonvulsants for cocaine dependence 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.