Severe early childhood caries vs Caries-free controls: Serum 25-hydroxyvitamin D level
In North America, children with S-ECC had lower serum 25(OH)D than caries-free children (WMD -13.28 nmol/l; ungraded).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Children with severe early childhood caries (S-ECC) vs Caries-free children Serum 25-hydroxyvitamin D level · Preschool children ≤6 years, North America · North America In North America, children with S-ECC had lower serum 25(OH)D than caries-free children (WMD -13.28 nmol/l; ungraded). The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis. (2024) All outcomes | MD -13.28 [-17.70, -8.87] | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| The Association Between Vitamin D and Early Childhood Caries: A Systematic Review and Meta-Analysis. 2024 All outcomes | December 2021 to February 2022 | 12 | Not applicable |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.