Question · asked by 1 review

Amiodarone vs other antiarrhythmics: Sudden cardiac death

It is very uncertain whether amiodarone changes sudden cardiac death compared with other antiarrhythmics (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Amiodarone vs other antiarrhythmics
Sudden cardiac death · participants with high risk of sudden cardiac death (secondary prevention)
It is very uncertain whether amiodarone changes sudden cardiac death compared with other antiarrhythmics (very low certainty).
Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death (2015) · Cochrane Headline outcomes only
RR 1.4 [0.56, 3.52]4 studies · 839 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.