Question · asked by 1 review

Agomelatine vs SSRI: Remission

It is very uncertain whether agomelatine changes remission rates The number of participants who achieved remission as… compared with SSRI (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Agomelatine vs SSRI
Remission rates The number of participants who achieved remission as defined by: a score of 7 or less on the 17‐item Hamilton Depression Rating Scale; 10 or less on the Montgomery‐Asberg Depression Rating Scale; 'not ill or borderline mentally ill... · patients with major depression
It is very uncertain whether agomelatine changes remission rates The number of participants who achieved remission as… compared with SSRI (very low certainty).
Agomelatine versus other antidepressive agents for major depression (2013) · Cochrane Headline outcomes only
RR 0.83 [0.68, 1.01]10 studies · 3826 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Agomelatine versus other antidepressive agents for major depression
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.