Question · asked by 1 review

Continuation vs discontinuation of antiplatelet therapy: Ischaemic events: peripheral thrombosis, cerebral myocardial infarction (within 30 days of surgery)

Continuation showed no clear difference in ischaemic events: peripheral thrombosis, cerebral myocardial… compared with discontinuation of antiplatelet therapy (low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Continuation vs discontinuation of antiplatelet therapy
Ischaemic events: peripheral thrombosis, cerebral myocardial infarction (within 30 days of surgery) · adults undergoing non‐cardiac surgery (including abdominal, urological, orthopaedic, and gynaecological surgery)
Continuation showed no clear difference in ischaemic events: peripheral thrombosis, cerebral myocardial… compared with discontinuation of antiplatelet therapy (low certainty).
Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults… (2018) · Cochrane Headline outcomes only
RR 0.67 [0.25, 1.77]4 studies · 616 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing non‐cardiac surgery
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.