Lamotrigine vs valproate: Normalisation of the EEG ‐ not reported
It is very uncertain whether lamotrigine changes normalisation of the EEG compared with valproate (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Lamotrigine vs valproate Normalisation of the EEG · absence seizures in children and adolescents It is very uncertain whether lamotrigine changes normalisation of the EEG compared with valproate (very low certainty). Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents (2021) · Cochrane Headline outcomes only | RR 2.39 [1.14, 5.04] | 1 study · 45 participants | Very low |
Lamotrigine vs valproate Normalization of the EEG · absence seizures in children and adolescents It is very uncertain whether lamotrigine changes normalization of the EEG compared with valproate (very low certainty). Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents (2019) · Cochrane Headline outcomes onlyearlier version CD003032.PUB4, superseded | RR 2.39 [1.14, 5.04] | 1 study · 45 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.