Summary of findings table ‐ Topical capsaicin vs vehicle: Risk for at least one adverse event per patient
- Population
- uraemic pruritus
- Intervention
- Summary of findings table ‐ Topical capsaicin
- Comparison
- vehicle
- Outcome
- Risk for at least one adverse event per patient
Topical capsaicin probably leads to higher risk for at least one adverse event per participant compared with vehicle (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Topical capsaicin vs vehicle Risk for at least one adverse event per participant · participants with uraemic pruritus (UP) Topical capsaicin probably leads to higher risk for at least one adverse event per participant compared with vehicle (moderate certainty). Pharmacological interventions for pruritus in adult palliative care patients (2016) · Cochrane Headline outcomes onlyearlier version CD008320.PUB3, superseded | RR 4.64 [2.05, 10.51] | 3 studies · 116 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Summary of findings table ‐ Topical capsaicin vs placebo · patients with chronic kidney disease (CKD) pruritus · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.