CR oxycodone vs IR oxycodone: Drowsiness/somnolence (Event rate during treatment, length of treatment varied across trials)
It is very uncertain whether CR oxycodone changes drowsiness/somnolence (Event rate during treatment, length of… compared with IR oxycodone (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
CR oxycodone vs IR oxycodone Drowsiness/somnolence (Event rate during treatment, length of treatment varied across trials) · adults with cancer‐related pain It is very uncertain whether CR oxycodone changes drowsiness/somnolence (Event rate during treatment, length of… compared with IR oxycodone (very low certainty). Oxycodone for cancer‐related pain (2022) · Cochrane Headline outcomes only | RR 1.03 [0.69, 1.54] | 3 studies · 317 participants | Very low |
CR oxycodone vs IR oxycodone Drowsiness/somnolence (Event rate) · adults with cancer‐related pain It is very uncertain whether CR oxycodone changes drowsiness/somnolence (Event rate) compared with IR oxycodone (very low certainty). Oxycodone for cancer‐related pain (2017) · Cochrane Headline outcomes onlyearlier version CD003870.PUB6, superseded | RR 1.03 [0.69, 1.54] | 3 studies · 317 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oxycodone for cancer‐related pain 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.