Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by A meta-analysis of pain intensity changes after placebo interventions in facial pain.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Effectiveness of Photobiomodulation in Temporomandibular Disorder-Related Pain Using a 635 nm Diode Laser: A Randomized, Blinded, and… Monteiro 2020 · Monteiro Luís, Ferreira Raquel, et al. · Photobiomodulation, photomedicine, and laser surgery PMID:32427553 | 2020 | 5 | none stated | not extracted yet |
| Effects of 8 weeks of masticatory muscles focused endurance exercises on women with oro-facial pain and temporomandibular disorders: A placebo… Barbosa 2019 · Barbosa Michelle Almeida, Tahara Ariany Klein, et al. · Journal of oral rehabilitation PMID:31099036 | 2019 | 4 | none stated | not extracted yet |
| Short-term transcutaneous electrical nerve stimulation reduces pain and improves the masticatory muscle activity in temporomandibular disorder… Ferreira 2017 · Ferreira Ana Paula de Lima, Costa Dayse Regina Alves da, et al. · Journal of applied oral science : revista FOB PMID:28403351 | 2017 | 4 | none stated | not extracted yet |
| Effect of Non-Ablative Non-Thermal CO2 Laser on Drug-Resistant Trigeminal Neuralgia: A Pilot Study. Rezazadeh 2023 · Rezazadeh Fahimeh, Borhani-Haghighi Afshin, et al. · Photobiomodulation, photomedicine, and laser surgery PMID:37335618 | 2023 | 3 | none stated | not extracted yet |
| Two doses of botulinum toxin type A for the treatment of trigeminal neuralgia: observation of therapeutic effect from a randomized, double-blind,… Zhang 2014 · Zhang Haifeng, Lian Yajun, et al. · The journal of headache and pain PMID:25263254 | 2014 | 3 | none stated | not extracted yet |
| Botulinum toxin-type A: could it be an effective treatment option in intractable trigeminal neuralgia? Shehata 2013 · Shehata Hatem S, El-Tamawy Mohamed S, et al. · The journal of headache and pain PMID:24251833 | 2013 | 3 | none stated | not extracted yet |
| Botulinum toxin type A for the treatment of trigeminal neuralgia: results from a randomized, double-blind, placebo-controlled trial. Wu 2012 · Wu Chuan-Jie, Lian Ya-Jun, et al. · Cephalalgia : an international journal of headache PMID:22492424 | 2012 | 3 | none stated | not extracted yet |
| Low-level laser therapy for treatment of temporomandibular joint pain: a double-blind and placebo-controlled trial. Emshoff 2008 · Emshoff Rüdiger, Bösch Renato, et al. · Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics PMID:18329580 | 2008 | 3 | none stated | not extracted yet |
| Does the Use of Botulinum Toxin in Treatment of Myofascial Pain Disorder of the Masseters and Temporalis Muscles Reduce Pain, Improve Function, or… Reeve 2024 · Reeve Gwendolyn S, Insel Owen, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:38228287 | 2024 | 2 | none stated | not extracted yet |
| Electroacupuncture and carbamazepine for patients with trigeminal neuralgia: a randomized, controlled, 2 × 2 factorial trial. Li 2024 · Li Rongrong, Sun Jing, et al. · Journal of neurology PMID:38816482 | 2024 | 2 | none stated | not extracted yet |
| Percutaneous Radiofrequency Ablation for Trigeminal Neuralgia Management: A Randomized, Double-Blinded, Sham-Controlled Clinical Trial. Mansano 2023 · Mansano André Marques, Frederico Thiago Nouer, et al. · Pain medicine (Malden, Mass.) PMID:36029256 | 2023 | 2 | none stated | not extracted yet |
| Low-level laser therapy (830 nm) on orthodontic pain: blinded randomized clinical trial. Martins 2019 · Martins Isabela Parsekian, Martins Renato Parsekian, et al. · Lasers in medical science PMID:29998356 | 2019 | 2 | none stated | not extracted yet |
| Therapeutic and Analgesic Efficacy of Laser in Conjunction With Pharmaceutical Therapy for Trigeminal Neuralgia. Ebrahimi 2018 · Ebrahimi Hooman, Najafi Shamsolmoulouk, et al. · Journal of lasers in medical sciences PMID:29399314 | 2018 | 2 | 1 | not extracted yet |
| Acupuncture Effect on Pain, Mouth Opening Limitation and on the Energy Meridians in Patients with Temporomandibular Dysfunction: A Randomized… Zotelli 2017 · Zotelli Vera Lr, Grillo Cássia M, et al. · Journal of acupuncture and meridian studies PMID:29078971 | 2017 | 2 | none stated | not extracted yet |
| Comparative study in patients with symptomatic internal derangements of the temporomandibular joint: analgesic outcomes of arthrocentesis with or… Sipahi 2015 · Sipahi A, Satilmis T, et al. · The British journal of oral & maxillofacial surgery PMID:25623934 | 2015 | 2 | none stated | not extracted yet |
| Controlling pain during orthodontic fixed appliance therapy with non-steroidal anti-inflammatory drugs (NSAID): a randomized, double-blinded,… Gupta 2014 · Gupta Mudit, Kandula Srinivas, et al. · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie PMID:25355194 | 2014 | 2 | none stated | not extracted yet |
| Patient-conducted anodal transcranial direct current stimulation of the motor cortex alleviates pain in trigeminal neuralgia. Hagenacker 2014 · Hagenacker Tim, Bude Vera, et al. · The journal of headache and pain PMID:25424567 | 2014 | 2 | none stated | not extracted yet |
| Acute treatment of trigeminal neuralgia with onabotulinum toxin A. Zúñiga 2013 · Zúñiga Carlos, Piedimonte Fabian, et al. · Clinical neuropharmacology PMID:24045604 | 2013 | 2 | none stated | not extracted yet |
| The adjunct therapeutic effect of lasers with medication in the management of orofacial pain: double blind randomized controlled trial. Amanat 2013 · Amanat Dariush, Ebrahimi Hooman, et al. · Photomedicine and laser surgery PMID:24102165 | 2013 | 2 | none stated | not extracted yet |
| No effect of glucosamine sulfate on osteoarthritis in the temporomandibular joints--a randomized, controlled, short-term study. Cahlin 2011 · Cahlin Birgitta Johansson, Dahlström Lars · Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics PMID:22001199 | 2011 | 2 | none stated | not extracted yet |
| Low level laser effects on pain to palpation and electromyographic activity in TMD patients: a double-blind, randomized, placebo-controlled study. Venezian 2010 · Venezian Giovana Cherubini, da Silva Marco Antônio Moreira Rodrigues, et al. · Cranio : the journal of craniomandibular practice PMID:20491229 | 2010 | 2 | none stated | not extracted yet |
| Efficacy of low-level laser therapy in the treatment of temporomandibular disorder. da Cunha 2008 · da Cunha Lia Alves, Firoozmand Leily Macedo, et al. · International dental journal PMID:18783114 | 2008 | 2 | none stated | not extracted yet |
| The efficacy of acupuncture in the treatment of temporomandibular joint myofascial pain: a randomised controlled trial. Smith 2007 · Smith Philip, Mosscrop Daniella, et al. · Journal of dentistry PMID:17095133 | 2007 | 2 | none stated | not extracted yet |
| Efficacy of preoperative oral rofecoxib in pain control for third molar surgery. Chiu 2005 · Chiu W K, Cheung L K · Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics PMID:15897845 | 2005 | 2 | none stated | not extracted yet |
| Topical clonazepam in stomatodynia: a randomised placebo-controlled study. Gremeau-Richard 2004 · Gremeau-Richard Christelle, Woda Alain, et al. · Pain PMID:15109507 | 2004 | 2 | none stated | not extracted yet |
| The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a… Menhinick 2004 · Menhinick K A, Gutmann J L, et al. · International endodontic journal PMID:15230906 | 2004 | 2 | 3 | not extracted yet |
| Use of sodium hyaluronate in treating temporomandibular joint disorders: a randomized, double-blind, placebo-controlled clinical trial. Bertolami 1993 · Bertolami C N, Gay T, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:8445463 | 1993 | 2 | none stated | not extracted yet |
| Effect of transcutaneous electrical nerve stimulation for controlling pain associated with orthodontic tooth movement. Roth 1986 · Roth P M, Thrash W J · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics PMID:3488674 | 1986 | 2 | none stated | not extracted yet |
| Bilateral focused ultrasound medial thalamotomies for trigeminal neuropathic pain: a randomized controlled study. Ishaque 2024 · Ishaque Mariam, Moosa Shayan, et al. · Journal of neurosurgery PMID:38157521 | 2024 | 1 | none stated | not extracted yet |
| Daily olive oil intake is feasible to reduce trigeminal neuralgia facial pain: A pilot study. Moreno 2024 · Moreno Melissa L, Percival Susan S, et al. · Nutrition research (New York, N.Y.) PMID:38306883 | 2024 | 1 | none stated | not extracted yet |
| Eptinezumab improved patient-reported outcomes in patients with migraine and medication-overuse headache: Subgroup analysis of the randomized… Starling 2023 · Starling Amaal J, Cowan Robert P, et al. · Headache PMID:36633219 | 2023 | 1 | none stated | not extracted yet |
| Remodeling dental anatomy vs sham therapy for chronic temporomandibular disorders. A placebo-controlled randomized clinical trial. Santana-Penín 2023 · Santana-Penín Urbano, Santana-Mora Urbano, et al. · Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft PMID:37302432 | 2023 | 1 | none stated | not extracted yet |
| Onabotulinum toxin A block of the sphenopalatine ganglion in patients with persistent idiopathic facial pain: a randomized, triple-blind,… Jamtøy 2023 · Jamtøy Kent A, Thorstensen Wenche M, et al. · Cephalalgia : an international journal of headache PMID:37435807 | 2023 | 1 | none stated | not extracted yet |
| Cardiovascular response to Gasserian ganglion ablation on trigeminal neuralgia under local anesthesia: a retrospective single-blind case-control… Zhao 2022 · Zhao Dingliang, Li Jing, et al. · BMC anesthesiology PMID:35410169 | 2022 | 1 | none stated | not extracted yet |
| Effects of photobiomodulation combined with orofacial myofunctional therapy on the quality of life of individuals with temporomandibular disorder. Dias 2022 · Dias Wellyda Cinthya Félix Gomes da Silva, Cavalcanti Renata Veiga Andersen, et al. · CoDAS PMID:35416889 | 2022 | 1 | none stated | not extracted yet |
| Migraine treatment with external concurrent occipital and trigeminal neurostimulation-A randomized controlled trial. Tepper 2022 · Tepper Stewart J, Grosberg Brian, et al. · Headache PMID:35748757 | 2022 | 1 | none stated | not extracted yet |
| Safety and efficacy of erenumab in patients with trigeminal neuralgia in Denmark: a double-blind, randomised, placebo-controlled, proof-of-concept… Schott Andersen 2022 · Schott Andersen Anne Sofie, Maarbjerg Stine, et al. · The Lancet. Neurology PMID:36113495 | 2022 | 1 | none stated | not extracted yet |
| Chronic Facial Pain in Fibromyalgia: May ElectroMagnetic Field Represent a Promising New Therapy? A Pilot Randomized-Controlled Study. Storari 2022 · Storari Marco, Zerman Nicoletta, et al. · International journal of environmental research and public health PMID:36612711 | 2022 | 1 | none stated | not extracted yet |
| Individualized Homeopathic Medicines in Chronic Rhinosinusitis: Randomized, Double-Blind, Placebo-Controlled Trial. Misra 2021 · Misra Pankhuri, Nayak Chintamani, et al. · Homeopathy : the journal of the Faculty of Homeopathy PMID:32869214 | 2021 | 1 | none stated | not extracted yet |
| Anodal transcranial direct current stimulation in chronic migraine and medication overuse headache: A pilot double-blind randomized sham-controlled… De Icco 2021 · De Icco R, Putortì A, et al. · Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology PMID:33271482 | 2021 | 1 | none stated | not extracted yet |
| Efficacy, tolerability, and safety of eptinezumab in patients with a dual diagnosis of chronic migraine and medication-overuse headache: Subgroup… Diener 2021 · Diener Hans-Christoph, Marmura Michael J, et al. · Headache PMID:33314079 | 2021 | 1 | none stated | not extracted yet |
| Effect of comorbid migraine on propranolol efficacy for painful TMD in a randomized controlled trial. Tchivileva 2021 · Tchivileva Inna E, Ohrbach Richard, et al. · Cephalalgia : an international journal of headache PMID:33560875 | 2021 | 1 | none stated | not extracted yet |
| Effectiveness of monopolar dielectric transmission of pulsed electromagnetic fields for multiple sclerosis-related pain: a pilot study. Hochsprung 2021 · Hochsprung A, Escudero-Uribe S, et al. · Neurologia PMID:34238526 | 2021 | 1 | none stated | not extracted yet |
| Evaluation of transcutaneous electrical nerve stimulation as an adjunct therapy in trigeminal neuralgia - a randomized double-blind… Bisla 2021 · Bisla Suman, Gupta Ambika, et al. · Journal of dental anesthesia and pain medicine PMID:34909474 | 2021 | 1 | none stated | not extracted yet |
| Effect of transcutaneous electrical nerve stimulation on jaw movement-evoked pain in patients with TMJ disc displacement without reduction and… Zhang 2020 · Zhang Yuanxiu, Zhang Jinglu, et al. · Acta odontologica Scandinavica PMID:31876451 | 2020 | 1 | none stated | not extracted yet |
| A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy of Steroid Supplementation After Temporomandibular Joint Arthrocentesis. Dolwick 2020 · Dolwick M Franklin, Diaz Daili, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:32201122 | 2020 | 1 | none stated | not extracted yet |
| Microcurrent technology for rapid relief of sinus pain: a randomized, placebo-controlled, double-blinded clinical trial. Maul 2019 · Maul Ximena A, Borchard Nicole A, et al. · International forum of allergy & rhinology PMID:30667597 | 2019 | 1 | none stated | not extracted yet |
| Revisited relationships between probable sleep bruxism and clinical muscle symptoms. Shimada 2019 · Shimada Akiko, Castrillon Eduardo E, et al. · Journal of dentistry PMID:30716450 | 2019 | 1 | none stated | not extracted yet |
| Effect of Acupuncture on Cognitive Function and Quality of Life in Patients With Idiopathic Trigeminal Neuralgia. Gao 2019 · Gao Jie, Zhao Chongfa, et al. · The Journal of nervous and mental disease PMID:30720599 | 2019 | 1 | none stated | not extracted yet |
| High-Voltage, Long-Duration Pulsed Radiofrequency on Gasserian Ganglion Improves Acute/Subacute Zoster-Related Trigeminal Neuralgia: A Randomized,… Wan 2019 · Wan Chengfu, Dong Dao-Song, et al. · Pain physician PMID:31337167 | 2019 | 1 | none stated | not extracted yet |