Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Periodontitis, Endothelial Dysfunction, and Systemic Inflammation: A Systematic Review and Meta-Analysis of Flow-Mediated Dilation.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Effect of periodontal therapy on endothelial function and serum biomarkers in patients with periodontitis and established cardiovascular disease: a… Molina 2025 · Molina Ana, Ambrosio Nagore, et al. · Frontiers in oral health PMID:39996093 | 2025 | 1 | none stated | not extracted yet |
| Endothelial Dysfunction, its Relationship with Chronic Periodontal Disease, and other Associated Risk Factors Velosa-Porras 2021 · Velosa-Porras Juliana, E. Arregoces Francina M., et al. · The Open Dentistry Journal DOI:10.2174/1874210602115010377 | 2021 | 1 | none stated | not extracted yet |
| Effect of advanced periodontal self-care in patients with early-stage periodontal diseases on endothelial function: An open-label, randomized… Okada 2021 · Okada Ayako, Murata Takatoshi, et al. · PloS one PMID:34555048 | 2021 | 1 | 1 | not extracted yet |
| Periodontitis is associated with endothelial dysfunction in a general population: a cross-sectional study. Holtfreter 2013 · Holtfreter Birte, Empen Klaus, et al. · PloS one PMID:24386401 | 2013 | 1 | none stated | not extracted yet |
| Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness. Piconi 2009 · Piconi Stefania, Trabattoni Daria, et al. · FASEB journal : official publication of the Federation of American Societies for Experimental Biology PMID:19074511 | 2009 | 1 | 1 | not extracted yet |
| Periodontal therapy reduces plasma levels of interleukin-6, C-reactive protein, and fibrinogen in patients with severe periodontitis and refractory… Vidal 2009 · Vidal Fábio, Figueredo Carlos Marcelo S, et al. · Journal of periodontology PMID:19405832 | 2009 | 1 | none stated | not extracted yet |
| Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients. Higashi 2008 · Higashi Yukihito, Goto Chikara, et al. · Hypertension (Dallas, Tex. : 1979) PMID:18039979 | 2008 | 1 | none stated | not extracted yet |
| Treatment of periodontitis and endothelial function. Tonetti 2007 · Tonetti Maurizio S, D'Aiuto Francesco, et al. · The New England journal of medicine PMID:17329698 | 2007 | 1 | 1 | not extracted yet |
| Periodontal care may improve endothelial function. Blum 2007 · Blum Arnon, Kryuger Konstantin, et al. · European journal of internal medicine PMID:17574103 | 2007 | 1 | 1 | not extracted yet |
| Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis. Seinost 2005 · Seinost Gerald, Wimmer Gernot, et al. · American heart journal PMID:15976787 | 2005 | 1 | 1 | not extracted yet |
| Periodontitis and systemic inflammation: control of the local infection is associated with a reduction in serum inflammatory markers. D'Aiuto 2004 · D'Aiuto F, Parkar M, et al. · Journal of dental research PMID:14742655 | 2004 | 1 | none stated | not extracted yet |
| The short-term effects of treatment of chronic periodontitis on circulating levels of endotoxin, C-reactive protein, tumor necrosis factor-alpha,… Ide 2004 · Ide Mark, Jagdev Daljit, et al. · Journal of periodontology PMID:15088881 | 2004 | 1 | none stated | not extracted yet |
| Endothelial dysfunction in patients with chronic periodontitis and its improvement after initial periodontal therapy. Mercanoglu 2004 · Mercanoglu Fehmi, Oflaz Hüseyin, et al. · Journal of periodontology PMID:15732873 | 2004 | 1 | 1 | not extracted yet |
| Periodontal disease is associated with brachial artery endothelial dysfunction and systemic inflammation. Amar 2003 · Amar Salomon, Gokce Noyan, et al. · Arteriosclerosis, thrombosis, and vascular biology PMID:12763762 | 2003 | 1 | none stated | not extracted yet |
| Velosa-Porras 2021 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |