Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Impact and efficacy of systemic antibiotics for peri-implant diseases treatment: A systematic review and meta-analysis on clinical and…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Adjunctive benefits of systemic metronidazole on non-surgical treatment of peri-implantitis. A randomized placebo-controlled clinical trial. Blanco 2022 · Blanco Carlota, Pico Alex, et al. · Journal of clinical periodontology PMID:34713471 | 2022 | 2 | 1 | not extracted yet |
| Non-surgical peri-implantitis treatment with or without systemic antibiotics: a randomized controlled clinical trial. Polymeri 2022 · Polymeri Angeliki, van der Horst Joyce, et al. · Clinical oral implants research PMID:35238084 | 2022 | 2 | 1 | not extracted yet |
| Systemic antibiotic therapy as an adjunct to non-surgical peri-implantitis treatment: A single-blind RCT. De Waal 2021 · De Waal Yvonne C M, Vangsted Tine E, et al. · Journal of clinical periodontology PMID:33939193 | 2021 | 2 | 1 | not extracted yet |
| Clinical efficacy of photodynamic therapy as an adjunct to mechanical debridement in the treatment of per-implantitis with abscess. Almohareb 2020 · Almohareb Thamer, Alhamoudi Nawaf, et al. · Photodiagnosis and photodynamic therapy PMID:32545150 | 2020 | 2 | none stated | not extracted yet |
| Microbiological and clinical effects of adjunctive systemic metronidazole and amoxicillin in the non-surgical treatment of peri-implantitis: 1 year… Shibli 2019 · Shibli Jamil Awad, Ferrari Daniel Sanchez, et al. · Brazilian oral research PMID:31576959 | 2019 | 2 | 1 | not extracted yet |
| Systemic Antibiotic Prophylaxis Adjunctive to Surgical Reconstructive Peri-Implantitis Treatment: A Retrospective Study. Ramanauskaite 2024 · Ramanauskaite Ausra, Saltzer Ioanna, et al. · Clinical implant dentistry and related research PMID:39676072 | 2025 | 1 | none stated | not extracted yet |
| Systemic antibiotics in the surgical treatment of peri-implantitis: A randomized placebo-controlled trial. Riben Grundstrom 2024 · Riben Grundström Caroline, Lund Bodil, et al. · Journal of clinical periodontology PMID:38699828 | 2024 | 1 | none stated | not extracted yet |
| Efficacy of Antibiotic Versus Probiotics As Adjuncts to Mechanical Debridement for the Treatment of Peri-Implant Mucositis. Alqahtani 2022 · Alqahtani Fawaz, Alshaikh Maha, et al. · The Journal of oral implantology PMID:33450748 | 2022 | 1 | none stated | not extracted yet |
| Effects of Implant Surface Debridement and Systemic Antibiotics on the Clinical and Microbiological Variables of Periimplantitis. Irshad 2021 · Irshad Muhammad, Alam Mohammad Khursheed, et al. · BioMed research international PMID:33553428 | 2021 | 1 | none stated | not extracted yet |
| Clinical and microbiological outcomes of photodynamic and systemic antimicrobial therapy in smokers with peri-implant inflammation. Al Deeb 2020 · Deeb Modhi Al, Alsahhaf Abdulaziz, et al. · Photodiagnosis and photodynamic therapy PMID:31689510 | 2020 | 1 | none stated | not extracted yet |
| The effects of Lactobacillus reuteri probiotics combined with azithromycin on peri-implantitis: A randomized placebo-controlled study. Tada 2018 · Tada Hiroaki, Masaki Chihiro, et al. · Journal of prosthodontic research PMID:28756115 | 2018 | 1 | none stated | not extracted yet |
| Randomized clinical trial of the effects of azithromycin use in the treatment of peri-implantitis. Gershenfeld 2018 · Gershenfeld L, Kalos A, et al. · Australian dental journal PMID:29679488 | 2018 | 1 | none stated | not extracted yet |
| Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. Hallstrom 2017 · Hallström Hadar, Persson G Rutger, et al. · Journal of clinical periodontology PMID:28836279 | 2017 | 1 | none stated | not extracted yet |
| Surgical treatment of peri-implantitis: 3-year results from a randomized controlled clinical trial. Carcuac 2017 · Carcuac Olivier, Derks Jan, et al. · Journal of clinical periodontology PMID:28902426 | 2017 | 1 | none stated | not extracted yet |
| Adjunctive Systemic and Local Antimicrobial Therapy in the Surgical Treatment of Peri-implantitis: A Randomized Controlled Clinical Trial. Carcuac 2016 · Carcuac O, Derks J, et al. · Journal of dental research PMID:26285807 | 2016 | 1 | none stated | not extracted yet |
| Full-mouth scaling and root planing combined with azithromycin to treat peri-implantitis. Gomi 2015 · Gomi K, Matsushima Y, et al. · Australian dental journal PMID:25439282 | 2015 | 1 | none stated | not extracted yet |
| Anti-infective surgical therapy of peri-implantitis. A 12-month prospective clinical study. Heitz-Mayfield 2012 · Heitz-Mayfield L J A, Salvi G E, et al. · Clinical oral implants research PMID:22092831 | 2012 | 1 | none stated | not extracted yet |
| Systemic antibiotics and debridement of peri-implant mucositis. A randomized clinical trial. Hallstrom 2012 · Hallström Hadar, Persson G Rutger, et al. · Journal of clinical periodontology PMID:22571225 | 2012 | 1 | none stated | not extracted yet |