evidencegaps
Primary study · included by 2 reviews

Microbiological and clinical effects of adjunctive systemic metronidazole and amoxicillin in the non-surgical treatment of peri-implantitis: 1 year follow-up.

Shibli 2019 · Shibli Jamil Awad, Ferrari Daniel Sanchez, Siroma Rafael Shinoske, et al. · Brazilian oral research · 2019

Included by

Impact and efficacy of systemic antibiotics for peri-implant diseases treatment: A systematic review and meta-analysis on clinical and microbiological outcomes.
Non-Cochrane · intervention · 2025 · cited as Shibli 2019 · Table 2; reference list

The review does not say which of its outcomes this study informs.

Risk-based efficacy of systemic and local antibiotics in nonsurgical treatment of peri-implantitis: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Shibli 2019 · Table 1; reference 38
Outcome this study informsPooled effectEvidenceCertainty
Probing depth (PD) reduction
Systemic or local antibiotics adjunctive to nonsurgical debridement vs Nonsurgical mechanical debridement alone
SMD -0.666 [-1.014, -0.318]6 studies · 325 participantsGRADE not reported

2 including reviews in total.