Studies

Primary studies

26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.

42 studies

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StudyYearReviewsReview outcomes linkedTrial data
Association between oral health and cognitive impairment in older adults: Insights from a Six-year prospective cohort study.
Chen et al. 2024 · Chen Jung-Tsu, Tsai Stephanie, et al. · Journal of dentistry
PMID:38801941
202421not extracted yet
Association between Tooth Loss and Alzheimer's Disease in a Nested Case-Control Study Based on a National Health Screening Cohort.
Kim 2021 · Kim Ji Hee, Oh Jae Keun, et al. · Journal of clinical medicine
PMID:34501210
202121not extracted yet
Association between tooth loss and the development of mild memory impairment in the elderly: the Fujiwara-kyo Study.
Okamoto 2015 · Okamoto Nozomi, Morikawa Masayuki, et al. · Journal of Alzheimer's disease : JAD
PMID:25362033
201523not extracted yet
Tooth loss explains income inequalities in dementia
Shimada 2025 · Shimada Satomi, Matsuyama Yusuke, et al. · Journal of Dentistry
DOI:10.1016/j.jdent.2024.105518
202512not extracted yet
Tooth loss explains income inequalities in dementia.
Shimada 2025 · Shimada Satomi, Matsuyama Yusuke, et al. · Journal of dentistry
PMID:39653269
202512not extracted yet
Associations between tooth loss, denture use, and dementia in older Taiwanese adults.
Chen 2025 · Chen Yi-Wen, Li Chung-Yi, et al. · Journal of the Chinese Medical Association : JCMA
PMID:39774060
202512not extracted yet
Number of Teeth and Dementia-free Life Expectancy: A 10-Year Follow-Up Study from the Japan Gerontological Evaluation Study
Kiuchi 2024 · Kiuchi Sakura, Matsuyama Yusuke, et al. · Journal of the American Medical Directors Association
DOI:10.1016/j.jamda.2024.105258
202412not extracted yet
Association between oral health and cognitive impairment in older adults: Insights from a Six-year prospective cohort study
Chen JT 2024 · Chen Jung-Tsu, Tsai Stephanie, et al. · Journal of Dentistry
DOI:10.1016/j.jdent.2024.105088
202411not extracted yet
Denture Use Mitigates the Cognitive Impact of Tooth Loss in Older Adults
Chou 2024 · Chou Yi-Chang, Weng Shih-Han, et al. · The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences
DOI:10.1093/gerona/glae248
202412not extracted yet
Associations among tooth loss, denture use, and dementia in older Taiwanese adults
Chen YW 2025 · Chen Yi-Wen, Li Chung-Yi, et al. · Journal of the Chinese Medical Association
DOI:10.1097/jcma.0000000000001171
202412not extracted yet
Poor oral health and dementia risk under time-varying confounding: A cohort study based on marginal structural models.
Kusama 2023 · Kusama Taro, Takeuchi Kenji, et al. · Journal of the American Geriatrics Society
PMID:38064294
202412not extracted yet
Association Between Reduced Posterior Occlusal Contact and Alzheimer's Disease Onset in Older Japanese Adults: Results from the LIFE Study.
Miyano 2024 · Miyano Takashi, Ayukawa Yasunori, et al. · Journal of Alzheimer's disease : JAD
PMID:38160352
202411not extracted yet
Number of Teeth and Dementia-free Life Expectancy: A 10-Year Follow-Up Study from the Japan Gerontological Evaluation Study.
Kiuchi 2024 · Kiuchi Sakura, Matsuyama Yusuke, et al. · Journal of the American Medical Directors Association
PMID:39276797
202412not extracted yet
Denture Use Mitigates the Cognitive Impact of Tooth Loss in Older Adults.
Chou 2024 · Chou Yi-Chang, Weng Shih-Han, et al. · The journals of gerontology. Series A, Biological sciences and medical sciences
PMID:39626020
202412not extracted yet
Oral frailty as a risk factor for mild cognitive impairment in community-dwelling older adults: Kashiwa study
Nagatani 2023 · Nagatani Miyuki, Tanaka Tomoki, et al. · Experimental Gerontology
DOI:10.1016/j.exger.2022.112075
202312not extracted yet
Association between Dental Diseases and Oral Hygiene Care and the Risk of Dementia: A Retrospective Cohort Study
Yoo JE 2023 · Yoo Jung Eun, Huh Youn, et al. · Journal of the American Medical Directors Association
DOI:10.1016/j.jamda.2023.08.011
202311not extracted yet
Association of tooth count with cognitive decline and dementia in the Finnish adult population
Asher 2023 · Asher Sam, Suominen Anna Liisa, et al. · Journal of Clinical Periodontology
DOI:10.1111/jcpe.13851
202314not extracted yet
Poor oral health and dementia risk under time‐varying confounding: A cohort study based on marginal structural models
Kusama 2024 · Kusama Taro, Takeuchi Kenji, et al. · Journal of the American Geriatrics Society
DOI:10.1111/jgs.18707
202312not extracted yet
Longitudinal association of edentulism with cognitive impairment, sarcopenia and all-cause mortality among older Chinese adults
Li 2023 · Li Yang, Huang Chuan-Long, et al. · BMC Oral Health
DOI:10.1186/s12903-023-03015-w
202311not extracted yet
Poor Oral Health as a Risk Factor for Dementia in a Swedish Population: A Cohort Study with 40 Years of Follow-Up
He 2023 · He Fei, Luo Huizi, et al. · Journal of Alzheimer's Disease
DOI:10.3233/jad-215177
202312not extracted yet
Association Between Reduced Posterior Occlusal Contact and Alzheimer’s Disease Onset in Older Japanese Adults: Results from the LIFE Study
Miyano 2024 · Miyano Takashi, Ayukawa Yasunori, et al. · Journal of Alzheimer’s Disease
DOI:10.3233/jad-230449
202311not extracted yet
Poor Oral Health Linked with Higher Risk of Alzheimer’s Disease
Kulkarni 2023 · Kulkarni Mihir S., Miller Brandi C., et al. · Brain Sciences
DOI:10.3390/brainsci13111555
202311not extracted yet
Oral frailty as a risk factor for mild cognitive impairment in community-dwelling older adults: Kashiwa study.
Nagatani 2023 · Nagatani Miyuki, Tanaka Tomoki, et al. · Experimental gerontology
PMID:36581224
202312not extracted yet
Poor Oral Health as a Risk Factor for Dementia in a Swedish Population: A Cohort Study with 40 Years of Follow-Up.
He 2023 · He Fei, Luo Huizi, et al. · Journal of Alzheimer's disease : JAD
PMID:36710668
202312not extracted yet
Longitudinal association of edentulism with cognitive impairment, sarcopenia and all-cause mortality among older Chinese adults.
Li 2023 · Li Yang, Huang Chuan-Long, et al. · BMC oral health
PMID:37244990
202311not extracted yet
Association of tooth count with cognitive decline and dementia in the Finnish adult population.
Asher 2023 · Asher Sam, Suominen Anna Liisa, et al. · Journal of clinical periodontology
PMID:37461219
202314not extracted yet
Association between Dental Diseases and Oral Hygiene Care and the Risk of Dementia: A Retrospective Cohort Study.
Yoo 2023 · Yoo Jung Eun, Huh Youn, et al. · Journal of the American Medical Directors Association
PMID:37709259
202311not extracted yet
Poor Oral Health Linked with Higher Risk of Alzheimer's Disease.
Kulkarni 2023 · Kulkarni Mihir S, Miller Brandi C, et al. · Brain sciences
PMID:38002515
202311not extracted yet
The Impact of Masticatory Function on Cognitive Impairment in Older Patients: A Population-Based Matched Case-Control Study
Ko 2022 · Ko Kyung-A, Park Jin-Young, et al. · Yonsei Medical Journal
DOI:10.3349/ymj.2022.63.8.783
202212not extracted yet
The Impact of Masticatory Function on Cognitive Impairment in Older Patients: A Population-Based Matched Case-Control Study.
Ko 2022 · Ko Kyung-A, Park Jin-Young, et al. · Yonsei medical journal
PMID:35914761
202212not extracted yet
Association between tooth loss rate and risk of mild cognitive impairment in older adults: a population-based longitudinal study
Xu 2021 · Xu Shuyu, Huang Xi, et al. · Aging
DOI:10.18632/aging.203504
202111not extracted yet
Association between Tooth Loss and Alzheimer’s Disease in a Nested Case–Control Study Based on a National Health Screening Cohort
Kim 2021 · Kim Ji Hee, Oh Jae Keun, et al. · Journal of Clinical Medicine
DOI:10.3390/jcm10173763
202111not extracted yet
Association between tooth loss rate and risk of mild cognitive impairment in older adults: a population-based longitudinal study.
Xu 2021 · Xu Shuyu, Huang Xi, et al. · Aging
PMID:34495870
202111not extracted yet
The effect of missing teeth on dementia in older people: a nationwide population-based cohort study in South Korea
Yoo JJ 2019 · Yoo Jin-Joo, Yoon Joon-Ho, et al. · BMC Oral Health
DOI:10.1186/s12903-019-0750-4
201911not extracted yet
The effect of missing teeth on dementia in older people: a nationwide population-based cohort study in South Korea.
Yoo 2019 · Yoo Jin-Joo, Yoon Joon-Ho, et al. · BMC oral health
PMID:31023356
201911not extracted yet
Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study
Dintica 2018 · Dintica Christina S., Rizzuto Debora, et al. · Neurobiology of Aging
DOI:10.1016/j.neurobiolaging.2018.03.003
201812not extracted yet
Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the…
Saito 2018 · Saito Sho, Ohi Takashi, et al. · BMC Oral Health
DOI:10.1186/s12903-018-0602-7
201811not extracted yet
Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study.
Dintica 2018 · Dintica Christina S, Rizzuto Debora, et al. · Neurobiology of aging
PMID:29609079
201812not extracted yet
Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the…
Saito 2018 · Saito Sho, Ohi Takashi, et al. · BMC oral health
PMID:30126407
201811not extracted yet
Association between Tooth Loss and the Development of Mild Memory Impairment in the Elderly: The Fujiwara-kyo Study
Okamoto 2015 · Okamoto Nozomi, Morikawa Masayuki, et al. · Journal of Alzheimer's Disease
DOI:10.3233/jad-141665
201512not extracted yet
Association Between Self-Reported Dental Health Status and Onset of Dementia
Yamamoto 2012 · Yamamoto Tatsuo, Kondo Katsunori, et al. · Psychosomatic Medicine
DOI:10.1097/psy.0b013e318246dffb
201212not extracted yet
Association between self-reported dental health status and onset of dementia: a 4-year prospective cohort study of older Japanese adults from the…
Yamamoto 2012 · Yamamoto Tatsuo, Kondo Katsunori, et al. · Psychosomatic medicine
PMID:22408130
201212not extracted yet