Primary study · included by 2 reviews

Association between tooth loss and the development of mild memory impairment in the elderly: the Fujiwara-kyo Study.

Okamoto 2015 · Okamoto Nozomi, Morikawa Masayuki, Tomioka Kimiko, et al. · Journal of Alzheimer's disease : JAD · 2015

Included by

Dentition-Cognition Relationship in Aging Populations: A Meta-Analysis of Longitudinal Data.
Non-Cochrane · aetiology · 2026 · cited as Okamoto 2015 · Fig. 2; Tables 1-2
Outcome this study informsPooled effectEvidenceCertainty
Mild cognitive impairment (MCI)
Tooth loss vs Fewer lost teeth / dentate (reference) · Mean follow-up 8.87 years across all included studies
OR 1.43 [1.10, 1.85]8 studiesGRADE not reported
Mild cognitive impairment (MCI)
Tooth loss vs Fewer lost teeth / dentate (reference) · Mean follow-up 8.87 years across all included studies
OR 1.40 [1.14, 1.71]9 studiesGRADE not reported
Mild cognitive impairment (MCI)
Edentulism vs Dentate (reference) · Mean follow-up 8.87 years across all included studies
OR 1.90 [1.07, 3.35]3 studiesGRADE not reported
Outcome this study informsPooled effectEvidenceCertainty
Mild cognitive impairment (MCI)
Periodontitis (most severe form reported) vs No or less severe periodontitis
OR 1.78 [0.73, 4.32]3 studiesGRADE not reported
Mild cognitive impairment (MCI)
Periodontitis (most severe form reported) vs No or less severe periodontitis
OR 1.27 [0.87, 1.86]5 studiesGRADE not reported
Mild cognitive impairment (MCI)
Periodontitis (most severe form reported) vs No or less severe periodontitis
OR 0.98 [0.78, 1.22]3 studiesGRADE not reported
Mild cognitive impairment (MCI)
Periodontitis (most severe form reported) vs No or less severe periodontitis
OR 2.78 [1.54, 5.02]2 studiesGRADE not reported
Mild cognitive impairment (MCI), cognitive decline or mild memory impairment
Periodontitis (most severe category reported) vs No periodontitis or less severe periodontitis
OR 2.41 [1.48, 3.93]4 studiesGRADE not reported
Mild cognitive impairment (MCI), cognitive decline or mild memory impairment
Periodontitis (most severe category reported) vs No periodontitis or less severe periodontitis
OR 1.36 [1.14, 1.64]3 studiesGRADE not reported
Mild cognitive impairment (MCI), cognitive decline or mild memory impairment
Periodontitis (most severe category reported) vs No periodontitis or less severe periodontitis
OR 3.79 [2.51, 5.74]2 studiesGRADE not reported
Mild cognitive impairment (MCI)
Periodontitis (most severe form reported) vs No or less severe periodontitis
OR 1.03 [0.79, 1.34]2 studiesGRADE not reported

2 including reviews in total.