Studies

Primary studies

26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.

68 studies

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StudyYearReviewsReview outcomes linkedTrial data
Prevention of medication-related osteonecrosis of the jaw: institutional insights from a retrospective study.
Chang 2025 · Chang Y S, Nanayakkara S, et al. · Australian dental journal
PMID:39670507
20251none statednot extracted yet
The role of leukocyte and platelet-rich fibrin in the prevention of medication-related osteonecrosis of the jaw, in patients requiring dental…
Besi et al. 2024 · Besi Eleni, Pitros Panagiotis · Oral and Maxillofacial Surgery
DOI:10.1007/s10006-023-01204-z
202411not extracted yet
Prevention of medication‐related osteonecrosis of the jaw: institutional insights from a retrospective study
Chang et al. 2025 · Chang YS, Nanayakkara S, et al. · Australian Dental Journal
DOI:10.1111/adj.13050
20241none statednot extracted yet
Reduction of <scp>MRONJ</scp> risk after exodontia by virtue of ozone infiltration: A randomized clinical trial
Di Fede et al. 2024 · Di Fede Olga, La Mantia Gaetano, et al. · Oral Diseases
DOI:10.1111/odi.15006
20241none statednot extracted yet
The role of leukocyte and platelet-rich fibrin in the prevention of medication-related osteonecrosis of the jaw, in patients requiring dental…
Besi 2024 · Besi Eleni, Pitros Panagiotis · Oral and maxillofacial surgery
PMID:38182917
202411not extracted yet
Reduction of MRONJ risk after exodontia by virtue of ozone infiltration: A randomized clinical trial.
Di Fede 2024 · Di Fede Olga, La Mantia Gaetano, et al. · Oral diseases
PMID:38807567
20241none statednot extracted yet
Pentoxifylline and tocopherol as prophylaxis for osteonecrosis of the jaw due to bone-modifying agents in patients with cancer submitted to tooth…
Megalhaes et al. 2023 · Magalhães Jackeline Mayara Inácio, da Motta Silveira Fabiana Moura, et al. · Supportive Care in Cancer
DOI:10.1007/s00520-023-07906-0
20231none statednot extracted yet
Comparison of Different Antibiotic Regimes for Preventive Tooth Extractions in Patients with Antiresorptive Intake—A Retrospective Cohort Study
Ristow et al. 2023 · Ristow Oliver, Rückschloß Thomas, et al. · Antibiotics
DOI:10.3390/antibiotics12060997
20231none statednot extracted yet
Efficacy of fibrin-rich platelets and leukocytes (L-PRF) in tissue repair in surgical oral procedures in patients using zoledronic acid-case-control…
Parise 2023 · Parise Guilherme Klein, Costa Brenda Nazareth, et al. · Oral and maxillofacial surgery
PMID:35739366
20231none statednot extracted yet
The effect of drug holiday before tooth extraction on the development of medication-related osteonecrosis of the jaw in cancer patients receiving…
Karaca 2023 · Karaca Çiğdem, Topaloğlu-Yasan Göknur, et al. · Journal of the Korean Association of Oral and Maxillofacial Surgeons
PMID:37114444
20231none statednot extracted yet
Comparison of Different Antibiotic Regimes for Preventive Tooth Extractions in Patients with Antiresorptive Intake-A Retrospective Cohort Study.
Ristow 2023 · Ristow Oliver, Rückschloß Thomas, et al. · Antibiotics (Basel, Switzerland)
PMID:37370316
20231none statednot extracted yet
Pentoxifylline and tocopherol as prophylaxis for osteonecrosis of the jaw due to bone-modifying agents in patients with cancer submitted to tooth…
Magalhães 2023 · Magalhães Jackeline Mayara Inácio, da Motta Silveira Fabiana Moura, et al. · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PMID:37436539
20231none statednot extracted yet
Efficacy of fibrin-rich platelets and leukocytes (L-PRF) in tissue repair in surgical oral procedures in patients using zoledronic acid—case–control…
Parise et al. 2022 · Parise Guilherme Klein, Costa Brenda Nazareth, et al. · Oral and Maxillofacial Surgery
DOI:10.1007/s10006-022-01094-7
20221none statednot extracted yet
Medication-related osteonecrosis of the jaw after tooth extraction in patients receiving pharmaceutical treatment for osteoporosis: A retrospective…
Seki et al. 2022 · Seki Keisuke, Kaneko Tadayoshi, et al. · Journal of Dental Sciences
DOI:10.1016/j.jds.2022.03.014
20221none statednot extracted yet
Incidence and risk factors associated to Medication-Related Osteo Necrosis of the Jaw (MRONJ) in patients with osteoporosis after tooth extractions.…
Cuozzo et al. 2022 · Cuozzo Alessandro, Iorio-Siciliano Vincenzo, et al. · Journal of Stomatology, Oral and Maxillofacial Surgery
DOI:10.1016/j.jormas.2022.03.020
20221none statednot extracted yet
Incidence and risk factors associated to Medication-Related Osteo Necrosis of the Jaw (MRONJ) in patients with osteoporosis after tooth extractions.…
Cuozzo 2022 · Cuozzo Alessandro, Iorio-Siciliano Vincenzo, et al. · Journal of stomatology, oral and maxillofacial surgery
PMID:35609780
20221none statednot extracted yet
Medication-related osteonecrosis of the jaw after tooth extraction in patients receiving pharmaceutical treatment for osteoporosis: A retrospective…
Seki 2022 · Seki Keisuke, Kaneko Tadayoshi, et al. · Journal of dental sciences
PMID:36299343
20221none statednot extracted yet
What is the Risk of Developing Medication-Related Osteonecrosis in Patients With Extraction Sockets Left to Heal by Secondary Intention? A…
Pippi et al. 2021 · Pippi Roberto, Giuliani Umberto, et al. · Journal of Oral and Maxillofacial Surgery
DOI:10.1016/j.joms.2021.05.031
202111not extracted yet
The incidence of medication-related osteonecrosis of the jaw following tooth extraction in patients prescribed oral bisphosphonates
Barry et al. 2021 · Barry Elizabeth, Taylor Talli, et al. · British Dental Journal
DOI:10.1038/s41415-021-3620-9
20211none statednot extracted yet
The Role of Platelet‐Rich Fibrin (PRF) in the Prevention of Medication‐Related Osteonecrosis of the Jaw (MRONJ)
Miranda et al. 2021 · Miranda Michele, Gianfreda Francesco, et al. · BioMed Research International
DOI:10.1155/2021/4948139
202111not extracted yet
Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake-A randomized pilot trial.
Ristow 2021 · Ristow Oliver, Rückschloß Thomas, et al. · Oral diseases
PMID:32875698
202111not extracted yet
The Role of Platelet-Rich Fibrin (PRF) in the Prevention of Medication-Related Osteonecrosis of the Jaw (MRONJ).
Miranda 2021 · Miranda Michele, Gianfreda Francesco, et al. · BioMed research international
PMID:34095295
202111not extracted yet
What is the Risk of Developing Medication-Related Osteonecrosis in Patients With Extraction Sockets Left to Heal by Secondary Intention? A…
Pippi 2021 · Pippi Roberto, Giuliani Umberto, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
PMID:34174218
202111not extracted yet
The incidence of medication-related osteonecrosis of the jaw following tooth extraction in patients prescribed oral bisphosphonates.
Barry 2021 · Barry Elizabeth, Taylor Talli, et al. · British dental journal
PMID:34815482
20211none statednot extracted yet
Alendronate or Zoledronic acid do not impair wound healing after tooth extraction in postmenopausal women with osteoporosis
Lesclous et al. 2020 · Lesclous Philippe, Cloitre Alexandra, et al. · Bone
DOI:10.1016/j.bone.2020.115412
20201none statednot extracted yet
Tooth extractions in patients under antiresorptive therapy for osteoporosis: Primary closure of the extraction socket with a mucoperiosteal flap…
Poxleitner et al. 2020 · Poxleitner Philipp, Steybe David, et al. · Journal of Cranio-Maxillofacial Surgery
DOI:10.1016/j.jcms.2020.02.006
20201none statednot extracted yet
Osteonecrosis of the jaw and dental extractions: A single-center experience
Sandhu et al. 2020 · Sandhu Shaiba, Salous Moaiad H., et al. · Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
DOI:10.1016/j.oooo.2020.07.001
202011not extracted yet
Antimicrobial photodynamic and photobiomodulation adjuvant therapies for prevention and treatment of medication-related osteonecrosis of the jaws:…
Tartaroti et al. 2020 · Tartaroti Natália Caroline, Marques Márcia Martins, et al. · Photodiagnosis and Photodynamic Therapy
DOI:10.1016/j.pdpdt.2020.101651
202011not extracted yet
Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake—A randomized pilot trial
Ristow et al. 2020 · Ristow Oliver, Rückschloß Thomas, et al. · Oral Diseases
DOI:10.1111/odi.13556
202011not extracted yet
Platelet-Rich Plasma (PRP) in Dental Extraction of Patients at Risk of Bisphosphonate-Related Osteonecrosis of the Jaws: A Two-Year Longitudinal Study
Mauceri 2020 · Mauceri Rodolfo, Panzarella Vera, et al. · Applied Sciences
DOI:10.3390/app10134487
202011not extracted yet
Antimicrobial photodynamic and photobiomodulation adjuvant therapies for prevention and treatment of medication-related osteonecrosis of the jaws:…
Tartaroti 2020 · Tartaroti Natália Caroline, Marques Márcia Martins, et al. · Photodiagnosis and photodynamic therapy
PMID:31923636
202011not extracted yet
Primary wound closure and perioperative antibiotic therapy for prevention of bisphosphonate-related osteonecrosis of the jaw after tooth extraction.
Spanou 2020 · Spanou Alexandra, Nelson Katja, et al. · Quintessence international (Berlin, Germany : 1985)
PMID:32020132
202011not extracted yet
Tooth extractions in patients under antiresorptive therapy for osteoporosis: Primary closure of the extraction socket with a mucoperiosteal flap…
Poxleitner 2020 · Poxleitner Philipp, Steybe David, et al. · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
PMID:32122726
20201none statednot extracted yet
Alendronate or Zoledronic acid do not impair wound healing after tooth extraction in postmenopausal women with osteoporosis.
Lesclous 2020 · Lesclous Philippe, Cloitre Alexandra, et al. · Bone
PMID:32404281
20201none statednot extracted yet
Osteonecrosis of the jaw and dental extractions: A single-center experience.
Sandhu 2020 · Sandhu Shaiba, Salous Moaiad H, et al. · Oral surgery, oral medicine, oral pathology and oral radiology
PMID:32723683
202011not extracted yet
Prevention of medication related osteonecrosis of the jaw after dentoalveolar surgery: An institution's experience.
Şahin 2020 · Şahin Onur, Tatar Birkan, et al. · Journal of clinical and experimental dentistry
PMID:32913575
202011not extracted yet
Adjunctive application of antimicrobial photodynamic therapy in the prevention of medication-related osteonecrosis of the jaw following…
Poli et al. 2019 · Poli Pier Paolo, Souza Francisley Ávila, et al. · Photodiagnosis and Photodynamic Therapy
DOI:10.1016/j.pdpdt.2019.05.037
20191none statednot extracted yet
Adjunctive application of antimicrobial photodynamic therapy in the prevention of medication-related osteonecrosis of the jaw following…
Poli 2019 · Poli Pier Paolo, Souza Francisley Ávila, et al. · Photodiagnosis and photodynamic therapy
PMID:31152878
20191none statednot extracted yet
Long-term oral bisphosphonates delay healing after tooth extraction: a single institutional prospective study
Shudo et al. 2018 · Shudo A., Kishimoto H., et al. · Osteoporosis International
DOI:10.1007/s00198-018-4621-7
20181none statednot extracted yet
Long-term oral bisphosphonates delay healing after tooth extraction: a single institutional prospective study.
Shudo 2018 · Shudo A, Kishimoto H, et al. · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
PMID:29967931
20181none statednot extracted yet
Primary wound closure after tooth extraction for prevention of medication-related osteonecrosis of the jaw in patients under denosumab.
Matsumoto 2017 · Matsumoto Akihiko, Sasaki Masanori, et al. · Clinical oral investigations
PMID:26924135
201711not extracted yet
Primary wound closure after tooth extraction for prevention of medication-related osteonecrosis of the jaw in patients under denosumab
Matsumoto et al. 2017 · Matsumoto Akihiko, Sasaki Masanori, et al. · Clinical Oral Investigations
DOI:10.1007/s00784-016-1762-y
201611not extracted yet
Incidence of bisphosphonate-related osteonecrosis of the jaw in high-risk patients undergoing surgical tooth extraction
Bodem et al. 2015 · Bodem Jens Philipp, Kargus Steffen, et al. · Journal of Cranio-Maxillofacial Surgery
DOI:10.1016/j.jcms.2015.02.018
20151none statednot extracted yet
Tooth extraction in patients receiving oral or intravenous bisphosphonate administration: A trigger for BRONJ development?
Otto et al. 2015 · Otto Sven, Tröltzsch Matthias, et al. · Journal of Cranio-Maxillofacial Surgery
DOI:10.1016/j.jcms.2015.03.039
201511not extracted yet
Incidence of bisphosphonate-related osteonecrosis of the jaw in high-risk patients undergoing surgical tooth extraction.
Bodem 2015 · Bodem Jens Philipp, Kargus Steffen, et al. · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
PMID:25841311
20151none statednot extracted yet
Tooth extraction in patients receiving oral or intravenous bisphosphonate administration: A trigger for BRONJ development?
Otto 2015 · Otto Sven, Tröltzsch Matthias, et al. · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
PMID:25958767
201511not extracted yet
A C-Terminal Crosslinking Telopeptide Test–Based Protocol for Patients on Oral Bisphosphonates Requiring Extraction: A Prospective Single-Center…
Hutcheson et al. 2014 · Hutcheson April, Cheng Andrew, et al. · Journal of Oral and Maxillofacial Surgery
DOI:10.1016/j.joms.2014.02.036
20141none statednot extracted yet
A C-terminal crosslinking telopeptide test-based protocol for patients on oral bisphosphonates requiring extraction: a prospective single-center…
Hutcheson 2014 · Hutcheson April, Cheng Andrew, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
PMID:24793621
20141none statednot extracted yet
Tooth extraction in osteoporotic patients taking oral bisphosphonates
Mozzati et al. 2013 · Mozzati M., Arata V., et al. · Osteoporosis International
DOI:10.1007/s00198-012-2239-8
20131none statednot extracted yet
Tooth Extractions in Intravenous Bisphosphonate-Treated Patients: A Refined Protocol
Scoletta et al. 2013 · Scoletta Matteo, Arata Valentina, et al. · Journal of Oral and Maxillofacial Surgery
DOI:10.1016/j.joms.2013.01.006
201311not extracted yet