Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Antibiotic Prophylaxis and Postoperative Therapy in Tooth Extractions for Patients at Risk of Medication-Related Osteonecrosis of the Jaw…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Prevention of medication-related osteonecrosis of the jaw: institutional insights from a retrospective study. Chang 2025 · Chang Y S, Nanayakkara S, et al. · Australian dental journal PMID:39670507 | 2025 | 1 | none stated | not extracted yet |
| The role of leukocyte and platelet-rich fibrin in the prevention of medication-related osteonecrosis of the jaw, in patients requiring dental… Besi et al. 2024 · Besi Eleni, Pitros Panagiotis · Oral and Maxillofacial Surgery DOI:10.1007/s10006-023-01204-z | 2024 | 1 | 1 | not extracted yet |
| Prevention of medication‐related osteonecrosis of the jaw: institutional insights from a retrospective study Chang et al. 2025 · Chang YS, Nanayakkara S, et al. · Australian Dental Journal DOI:10.1111/adj.13050 | 2024 | 1 | none stated | not extracted yet |
| Reduction of <scp>MRONJ</scp> risk after exodontia by virtue of ozone infiltration: A randomized clinical trial Di Fede et al. 2024 · Di Fede Olga, La Mantia Gaetano, et al. · Oral Diseases DOI:10.1111/odi.15006 | 2024 | 1 | none stated | not extracted yet |
| The role of leukocyte and platelet-rich fibrin in the prevention of medication-related osteonecrosis of the jaw, in patients requiring dental… Besi 2024 · Besi Eleni, Pitros Panagiotis · Oral and maxillofacial surgery PMID:38182917 | 2024 | 1 | 1 | not extracted yet |
| Reduction of MRONJ risk after exodontia by virtue of ozone infiltration: A randomized clinical trial. Di Fede 2024 · Di Fede Olga, La Mantia Gaetano, et al. · Oral diseases PMID:38807567 | 2024 | 1 | none stated | not extracted yet |
| Pentoxifylline and tocopherol as prophylaxis for osteonecrosis of the jaw due to bone-modifying agents in patients with cancer submitted to tooth… Megalhaes et al. 2023 · Magalhães Jackeline Mayara Inácio, da Motta Silveira Fabiana Moura, et al. · Supportive Care in Cancer DOI:10.1007/s00520-023-07906-0 | 2023 | 1 | none stated | not extracted yet |
| Comparison of Different Antibiotic Regimes for Preventive Tooth Extractions in Patients with Antiresorptive Intake—A Retrospective Cohort Study Ristow et al. 2023 · Ristow Oliver, Rückschloß Thomas, et al. · Antibiotics DOI:10.3390/antibiotics12060997 | 2023 | 1 | none stated | not extracted yet |
| Efficacy of fibrin-rich platelets and leukocytes (L-PRF) in tissue repair in surgical oral procedures in patients using zoledronic acid-case-control… Parise 2023 · Parise Guilherme Klein, Costa Brenda Nazareth, et al. · Oral and maxillofacial surgery PMID:35739366 | 2023 | 1 | none stated | not extracted yet |
| The effect of drug holiday before tooth extraction on the development of medication-related osteonecrosis of the jaw in cancer patients receiving… Karaca 2023 · Karaca Çiğdem, Topaloğlu-Yasan Göknur, et al. · Journal of the Korean Association of Oral and Maxillofacial Surgeons PMID:37114444 | 2023 | 1 | none stated | not extracted yet |
| Comparison of Different Antibiotic Regimes for Preventive Tooth Extractions in Patients with Antiresorptive Intake-A Retrospective Cohort Study. Ristow 2023 · Ristow Oliver, Rückschloß Thomas, et al. · Antibiotics (Basel, Switzerland) PMID:37370316 | 2023 | 1 | none stated | not extracted yet |
| Pentoxifylline and tocopherol as prophylaxis for osteonecrosis of the jaw due to bone-modifying agents in patients with cancer submitted to tooth… Magalhães 2023 · Magalhães Jackeline Mayara Inácio, da Motta Silveira Fabiana Moura, et al. · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer PMID:37436539 | 2023 | 1 | none stated | not extracted yet |
| Efficacy of fibrin-rich platelets and leukocytes (L-PRF) in tissue repair in surgical oral procedures in patients using zoledronic acid—case–control… Parise et al. 2022 · Parise Guilherme Klein, Costa Brenda Nazareth, et al. · Oral and Maxillofacial Surgery DOI:10.1007/s10006-022-01094-7 | 2022 | 1 | none stated | not extracted yet |
| Medication-related osteonecrosis of the jaw after tooth extraction in patients receiving pharmaceutical treatment for osteoporosis: A retrospective… Seki et al. 2022 · Seki Keisuke, Kaneko Tadayoshi, et al. · Journal of Dental Sciences DOI:10.1016/j.jds.2022.03.014 | 2022 | 1 | none stated | not extracted yet |
| Incidence and risk factors associated to Medication-Related Osteo Necrosis of the Jaw (MRONJ) in patients with osteoporosis after tooth extractions.… Cuozzo et al. 2022 · Cuozzo Alessandro, Iorio-Siciliano Vincenzo, et al. · Journal of Stomatology, Oral and Maxillofacial Surgery DOI:10.1016/j.jormas.2022.03.020 | 2022 | 1 | none stated | not extracted yet |
| Incidence and risk factors associated to Medication-Related Osteo Necrosis of the Jaw (MRONJ) in patients with osteoporosis after tooth extractions.… Cuozzo 2022 · Cuozzo Alessandro, Iorio-Siciliano Vincenzo, et al. · Journal of stomatology, oral and maxillofacial surgery PMID:35609780 | 2022 | 1 | none stated | not extracted yet |
| Medication-related osteonecrosis of the jaw after tooth extraction in patients receiving pharmaceutical treatment for osteoporosis: A retrospective… Seki 2022 · Seki Keisuke, Kaneko Tadayoshi, et al. · Journal of dental sciences PMID:36299343 | 2022 | 1 | none stated | not extracted yet |
| What is the Risk of Developing Medication-Related Osteonecrosis in Patients With Extraction Sockets Left to Heal by Secondary Intention? A… Pippi et al. 2021 · Pippi Roberto, Giuliani Umberto, et al. · Journal of Oral and Maxillofacial Surgery DOI:10.1016/j.joms.2021.05.031 | 2021 | 1 | 1 | not extracted yet |
| The incidence of medication-related osteonecrosis of the jaw following tooth extraction in patients prescribed oral bisphosphonates Barry et al. 2021 · Barry Elizabeth, Taylor Talli, et al. · British Dental Journal DOI:10.1038/s41415-021-3620-9 | 2021 | 1 | none stated | not extracted yet |
| The Role of Platelet‐Rich Fibrin (PRF) in the Prevention of Medication‐Related Osteonecrosis of the Jaw (MRONJ) Miranda et al. 2021 · Miranda Michele, Gianfreda Francesco, et al. · BioMed Research International DOI:10.1155/2021/4948139 | 2021 | 1 | 1 | not extracted yet |
| Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake-A randomized pilot trial. Ristow 2021 · Ristow Oliver, Rückschloß Thomas, et al. · Oral diseases PMID:32875698 | 2021 | 1 | 1 | not extracted yet |
| The Role of Platelet-Rich Fibrin (PRF) in the Prevention of Medication-Related Osteonecrosis of the Jaw (MRONJ). Miranda 2021 · Miranda Michele, Gianfreda Francesco, et al. · BioMed research international PMID:34095295 | 2021 | 1 | 1 | not extracted yet |
| What is the Risk of Developing Medication-Related Osteonecrosis in Patients With Extraction Sockets Left to Heal by Secondary Intention? A… Pippi 2021 · Pippi Roberto, Giuliani Umberto, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:34174218 | 2021 | 1 | 1 | not extracted yet |
| The incidence of medication-related osteonecrosis of the jaw following tooth extraction in patients prescribed oral bisphosphonates. Barry 2021 · Barry Elizabeth, Taylor Talli, et al. · British dental journal PMID:34815482 | 2021 | 1 | none stated | not extracted yet |
| Alendronate or Zoledronic acid do not impair wound healing after tooth extraction in postmenopausal women with osteoporosis Lesclous et al. 2020 · Lesclous Philippe, Cloitre Alexandra, et al. · Bone DOI:10.1016/j.bone.2020.115412 | 2020 | 1 | none stated | not extracted yet |
| Tooth extractions in patients under antiresorptive therapy for osteoporosis: Primary closure of the extraction socket with a mucoperiosteal flap… Poxleitner et al. 2020 · Poxleitner Philipp, Steybe David, et al. · Journal of Cranio-Maxillofacial Surgery DOI:10.1016/j.jcms.2020.02.006 | 2020 | 1 | none stated | not extracted yet |
| Osteonecrosis of the jaw and dental extractions: A single-center experience Sandhu et al. 2020 · Sandhu Shaiba, Salous Moaiad H., et al. · Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology DOI:10.1016/j.oooo.2020.07.001 | 2020 | 1 | 1 | not extracted yet |
| Antimicrobial photodynamic and photobiomodulation adjuvant therapies for prevention and treatment of medication-related osteonecrosis of the jaws:… Tartaroti et al. 2020 · Tartaroti Natália Caroline, Marques Márcia Martins, et al. · Photodiagnosis and Photodynamic Therapy DOI:10.1016/j.pdpdt.2020.101651 | 2020 | 1 | 1 | not extracted yet |
| Wound closure and alveoplasty after preventive tooth extractions in patients with antiresorptive intake—A randomized pilot trial Ristow et al. 2020 · Ristow Oliver, Rückschloß Thomas, et al. · Oral Diseases DOI:10.1111/odi.13556 | 2020 | 1 | 1 | not extracted yet |
| Platelet-Rich Plasma (PRP) in Dental Extraction of Patients at Risk of Bisphosphonate-Related Osteonecrosis of the Jaws: A Two-Year Longitudinal Study Mauceri 2020 · Mauceri Rodolfo, Panzarella Vera, et al. · Applied Sciences DOI:10.3390/app10134487 | 2020 | 1 | 1 | not extracted yet |
| Antimicrobial photodynamic and photobiomodulation adjuvant therapies for prevention and treatment of medication-related osteonecrosis of the jaws:… Tartaroti 2020 · Tartaroti Natália Caroline, Marques Márcia Martins, et al. · Photodiagnosis and photodynamic therapy PMID:31923636 | 2020 | 1 | 1 | not extracted yet |
| Primary wound closure and perioperative antibiotic therapy for prevention of bisphosphonate-related osteonecrosis of the jaw after tooth extraction. Spanou 2020 · Spanou Alexandra, Nelson Katja, et al. · Quintessence international (Berlin, Germany : 1985) PMID:32020132 | 2020 | 1 | 1 | not extracted yet |
| Tooth extractions in patients under antiresorptive therapy for osteoporosis: Primary closure of the extraction socket with a mucoperiosteal flap… Poxleitner 2020 · Poxleitner Philipp, Steybe David, et al. · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery PMID:32122726 | 2020 | 1 | none stated | not extracted yet |
| Alendronate or Zoledronic acid do not impair wound healing after tooth extraction in postmenopausal women with osteoporosis. Lesclous 2020 · Lesclous Philippe, Cloitre Alexandra, et al. · Bone PMID:32404281 | 2020 | 1 | none stated | not extracted yet |
| Osteonecrosis of the jaw and dental extractions: A single-center experience. Sandhu 2020 · Sandhu Shaiba, Salous Moaiad H, et al. · Oral surgery, oral medicine, oral pathology and oral radiology PMID:32723683 | 2020 | 1 | 1 | not extracted yet |
| Prevention of medication related osteonecrosis of the jaw after dentoalveolar surgery: An institution's experience. Şahin 2020 · Şahin Onur, Tatar Birkan, et al. · Journal of clinical and experimental dentistry PMID:32913575 | 2020 | 1 | 1 | not extracted yet |
| Adjunctive application of antimicrobial photodynamic therapy in the prevention of medication-related osteonecrosis of the jaw following… Poli et al. 2019 · Poli Pier Paolo, Souza Francisley Ávila, et al. · Photodiagnosis and Photodynamic Therapy DOI:10.1016/j.pdpdt.2019.05.037 | 2019 | 1 | none stated | not extracted yet |
| Adjunctive application of antimicrobial photodynamic therapy in the prevention of medication-related osteonecrosis of the jaw following… Poli 2019 · Poli Pier Paolo, Souza Francisley Ávila, et al. · Photodiagnosis and photodynamic therapy PMID:31152878 | 2019 | 1 | none stated | not extracted yet |
| Long-term oral bisphosphonates delay healing after tooth extraction: a single institutional prospective study Shudo et al. 2018 · Shudo A., Kishimoto H., et al. · Osteoporosis International DOI:10.1007/s00198-018-4621-7 | 2018 | 1 | none stated | not extracted yet |
| Long-term oral bisphosphonates delay healing after tooth extraction: a single institutional prospective study. Shudo 2018 · Shudo A, Kishimoto H, et al. · Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA PMID:29967931 | 2018 | 1 | none stated | not extracted yet |
| Primary wound closure after tooth extraction for prevention of medication-related osteonecrosis of the jaw in patients under denosumab. Matsumoto 2017 · Matsumoto Akihiko, Sasaki Masanori, et al. · Clinical oral investigations PMID:26924135 | 2017 | 1 | 1 | not extracted yet |
| Primary wound closure after tooth extraction for prevention of medication-related osteonecrosis of the jaw in patients under denosumab Matsumoto et al. 2017 · Matsumoto Akihiko, Sasaki Masanori, et al. · Clinical Oral Investigations DOI:10.1007/s00784-016-1762-y | 2016 | 1 | 1 | not extracted yet |
| Incidence of bisphosphonate-related osteonecrosis of the jaw in high-risk patients undergoing surgical tooth extraction Bodem et al. 2015 · Bodem Jens Philipp, Kargus Steffen, et al. · Journal of Cranio-Maxillofacial Surgery DOI:10.1016/j.jcms.2015.02.018 | 2015 | 1 | none stated | not extracted yet |
| Tooth extraction in patients receiving oral or intravenous bisphosphonate administration: A trigger for BRONJ development? Otto et al. 2015 · Otto Sven, Tröltzsch Matthias, et al. · Journal of Cranio-Maxillofacial Surgery DOI:10.1016/j.jcms.2015.03.039 | 2015 | 1 | 1 | not extracted yet |
| Incidence of bisphosphonate-related osteonecrosis of the jaw in high-risk patients undergoing surgical tooth extraction. Bodem 2015 · Bodem Jens Philipp, Kargus Steffen, et al. · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery PMID:25841311 | 2015 | 1 | none stated | not extracted yet |
| Tooth extraction in patients receiving oral or intravenous bisphosphonate administration: A trigger for BRONJ development? Otto 2015 · Otto Sven, Tröltzsch Matthias, et al. · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery PMID:25958767 | 2015 | 1 | 1 | not extracted yet |
| A C-Terminal Crosslinking Telopeptide Test–Based Protocol for Patients on Oral Bisphosphonates Requiring Extraction: A Prospective Single-Center… Hutcheson et al. 2014 · Hutcheson April, Cheng Andrew, et al. · Journal of Oral and Maxillofacial Surgery DOI:10.1016/j.joms.2014.02.036 | 2014 | 1 | none stated | not extracted yet |
| A C-terminal crosslinking telopeptide test-based protocol for patients on oral bisphosphonates requiring extraction: a prospective single-center… Hutcheson 2014 · Hutcheson April, Cheng Andrew, et al. · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons PMID:24793621 | 2014 | 1 | none stated | not extracted yet |
| Tooth extraction in osteoporotic patients taking oral bisphosphonates Mozzati et al. 2013 · Mozzati M., Arata V., et al. · Osteoporosis International DOI:10.1007/s00198-012-2239-8 | 2013 | 1 | none stated | not extracted yet |
| Tooth Extractions in Intravenous Bisphosphonate-Treated Patients: A Refined Protocol Scoletta et al. 2013 · Scoletta Matteo, Arata Valentina, et al. · Journal of Oral and Maxillofacial Surgery DOI:10.1016/j.joms.2013.01.006 | 2013 | 1 | 1 | not extracted yet |