Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Malignant Transformation of Oral Leukoplakia and Proliferative Verrucous Leukoplakia and Its Biomarker Predictors: A Systematic Umbrella…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Salivary micro RNA as a potential biomarker in oral potentially malignant disorders: A systematic review. Maheswari 2018 · Maheswari T N Uma, Venugopal Archana, et al. · Tzu chi medical journal PMID:29875583 | 2018 | 2 | none stated | not extracted yet |
| Malignant transformation of oral leukoplakia: Systematic review and comprehensive meta-analysis. Pimenta-Barros 2025 · Pimenta-Barros Liliana Aparecida, Ramos-García Pablo, et al. · Oral diseases PMID:39314164 | 2025 | 1 | none stated | not extracted yet |
| Gingival Proliferative Verrucous Leukoplakia and Cancer: A Systematic Review With Meta-Analysis. Vergier 2025 · Vergier Valentin, Porporatti André Luís, et al. · Oral diseases PMID:39385511 | 2025 | 1 | none stated | not extracted yet |
| DNA ploidy status as a predictor for malignant transformation in oral leukoplakia: a systematic review and meta-analysis. Thakkar 2025 · Thakkar Nandisha, Mane Deepa R, et al. · Oral surgery, oral medicine, oral pathology and oral radiology PMID:39837746 | 2025 | 1 | 1 | not extracted yet |
| Predictive Value of the Loss of pRb Expression in the Malignant Transformation Risk of Oral Potentially Malignant Disorders: A Systematic Review and… Lopez-Ansio 2025 · López-Ansio María, Ramos-García Pablo, et al. · Cancers PMID:39858110 | 2025 | 1 | 1 | not extracted yet |
| Malignant transformation of proliferative Verrucous Leukoplakia-systematic review & meta-analysis. Mohideen 2025 · Mohideen Khadijah, Ghosh Snehashish, et al. · BMC oral health PMID:39893387 | 2025 | 1 | none stated | not extracted yet |
| Tissue Biomarkers for Predicting the Risk of Oral Cancer in Patients Diagnosed With Oral Leukoplakia: A Systematic Review of the Past 4 Years. Monteiro 2025 · Monteiro Luís, Rocha Elia, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:40200649 | 2025 | 1 | none stated | not extracted yet |
| Significance of Epidermal Growth Factor Receptor (EGFR) upregulation in the prediction of the malignant transformation risk in oral potentially… Civico-Ortega 2025 · Cívico-Ortega José Luis, Ramos-García Pablo, et al. · Frontiers in oral health PMID:40213513 | 2025 | 1 | 1 | not extracted yet |
| Podoplanin could be a predictive biomarker of the risk of patients with oral leukoplakia to develop oral cancer: A systematic review and… Monteiro 2024 · Monteiro Luis, Mariano Lorena C, et al. · Oral diseases PMID:36103586 | 2024 | 1 | 1 | not extracted yet |
| Potential noninvasive biomarkers for the malignant transformation of oral leukoplakia: A systematic review and meta-analysis. Huang 2023 · Huang Yan, Zhang Qiufang, et al. · Cancer medicine PMID:37199052 | 2023 | 1 | none stated | not extracted yet |
| Malignant transformation rate of oral leukoplakia in the past 20 years: A systematic review and meta-analysis. Guan 2023 · Guan Jing-Yao, Luo Yong-Hua, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:37224426 | 2023 | 1 | none stated | not extracted yet |
| Assessment of Ploidy Status in Oral Potentially Malignant Disorders - A Systematic Review. Annapoorani 2023 · Annapoorani S, Gururaj N, et al. · Journal of pharmacy & bioallied sciences PMID:37654386 | 2023 | 1 | none stated | not extracted yet |
| Malignant development of proliferative verrucous/multifocal leukoplakia: A critical systematic review, meta-analysis and proposal of diagnostic… Ibanez 2022 · Lafuente Ibáñez de Mendoza Irene, Lorenzo Pouso Alejandro I, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:34558734 | 2022 | 1 | none stated | not extracted yet |
| Significance of p53 overexpression in the prediction of the malignant transformation risk of oral potentially malignant disorders: A systematic… Ramos-Garcia 2022 · Ramos-García Pablo, González-Moles Miguel Ángel, et al. · Oral oncology PMID:35091134 | 2022 | 1 | 1 | not extracted yet |
| Clinical predictors of malignant transformation and recurrence in oral potentially malignant disorders: A systematic review and meta-analysis. de Pauli Paglioni 2022 · Paglioni Mariana de Pauli, Khurram Syed Ali, et al. · Oral surgery, oral medicine, oral pathology and oral radiology PMID:36153299 | 2022 | 1 | none stated | not extracted yet |
| World Workshop on Oral Medicine VII: Prognostic biomarkers in oral leukoplakia and proliferative verrucous leukoplakia-A systematic review of… Celentano 2021 · Celentano Antonio, Glurich Ingrid, et al. · Oral diseases PMID:32306449 | 2021 | 1 | none stated | not extracted yet |
| Malignant transformation of oral leukoplakia: Systematic review and meta-analysis of the last 5 years. Aguirre-Urizar 2021 · Aguirre-Urizar José M, Lafuente-Ibáñez de Mendoza Irene, et al. · Oral diseases PMID:33606345 | 2021 | 1 | none stated | not extracted yet |
| Malignant transformation of oral proliferative verrucous leukoplakia: A systematic review and meta-analysis. Ramos-Garcia 2021 · Ramos-García Pablo, González-Moles Miguel Ángel, et al. · Oral diseases PMID:34009718 | 2021 | 1 | none stated | not extracted yet |
| Binary and WHO dysplasia grading systems for the prediction of malignant transformation of oral leukoplakia and erythroplakia: a systematic review… Freitas Silva 2021 · de Freitas Silva Brunno Santos, Batista Danielle Coelho Ribeiro, et al. · Clinical oral investigations PMID:34050426 | 2021 | 1 | 1 | not extracted yet |
| Oral Proliferative Verrucous Leukoplakia: Progression to Malignancy and Clinical Implications. Systematic Review and Meta-Analysis. Palaia 2021 · Palaia Gaspare, Bellisario Amelia, et al. · Cancers PMID:34439238 | 2021 | 1 | none stated | not extracted yet |
| A Systematic Review of MicroRNA Signatures Associated with the Progression of Leukoplakia with and without Epithelial Dysplasia. Kaunein 2021 · Kaunein Nadia, Ramani Rishi Sanjay, et al. · Biomolecules PMID:34944523 | 2021 | 1 | none stated | not extracted yet |
| Potentially malignant disorders of the oral cavity and oral dysplasia: A systematic review and meta-analysis of malignant transformation rate by… Iocca 2020 · Iocca Oreste, Sollecito Thomas P, et al. · Head & neck PMID:31803979 | 2020 | 1 | none stated | not extracted yet |
| Oral potentially malignant disorders: A comprehensive review on clinical aspects and management. Warnakulasuriya 2020 · Warnakulasuriya Saman · Oral oncology PMID:31981993 | 2020 | 1 | none stated | not extracted yet |
| Malignant transformation rate of oral leukoplakia-systematic review. Pinto 2020 · Pinto Ana Catarina, Caramês João, et al. · Oral surgery, oral medicine, oral pathology and oral radiology PMID:32249069 | 2020 | 1 | none stated | not extracted yet |
| World Workshop on Oral Medicine VII: Prognostic biomarkers in oral leukoplakia: A systematic review of longitudinal studies. Villa 2019 · Villa Alessandro, Celentano Antonio, et al. · Oral diseases PMID:31140698 | 2019 | 1 | none stated | not extracted yet |
| Meta-analysis of the predictive value of DNA aneuploidy in malignant transformation of oral potentially malignant disorders. Alaizari 2018 · Alaizari Nader A, Sperandio Marcelo, et al. · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:28612463 | 2018 | 1 | 1 | not extracted yet |
| Malignant transformation of oral leukoplakia: a systematic review of observational studies. Warnakulasuriya 2016 · Warnakulasuriya S, Ariyawardana A · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology PMID:26189354 | 2016 | 1 | none stated | not extracted yet |
| Gene expression profiling for the purposes of biomarker discovery in oral potentially malignant lesions: a systematic review. AbdulMajeed 2013 · Abdulmajeed Ahmad A, Farah Camile S · Clinical Medicine Insights. Oncology PMID:24250244 | 2013 | 1 | none stated | not extracted yet |