evidencegaps
Primary study · included by 1 review

Significance of Epidermal Growth Factor Receptor (EGFR) upregulation in the prediction of the malignant transformation risk in oral potentially malignant disorders: a systematic review and meta-analysis.

Civico-Ortega 2025 · Cívico-Ortega José Luis, Ramos-García Pablo, González-Moles Miguel Ángel · Frontiers in oral health · 2025

Included by

Malignant Transformation of Oral Leukoplakia and Proliferative Verrucous Leukoplakia and Its Biomarker Predictors: A Systematic Umbrella Review.
Non-Cochrane · prognostic · 2026 · cited as Civico-Ortega 2025 · Supplementary Table 3; ref 49
Outcome this study informsPooled effectEvidenceCertainty
Malignant transformation of OPMD
EGFR overexpression vs No EGFR overexpression
RR 2.17 [1.73, 2.73]8 studies · 653 participantsModerate

1 including review in total.