Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Chemoprophylaxis effect of EGCG on various digestive system diseases: a systematic review and meta-analysis.. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Hepatotoxicity of high oral dose (−)-epigallocatechin-3-gallate in mice Lambert 2010 · Lambert Joshua D., Kennett Mary J., et al. · Food and Chemical Toxicology DOI:10.1016/j.fct.2009.10.030 | 2010 | 1 | none stated | not extracted yet |
| Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice. Lambert 2010 · Lambert Joshua D, Kennett Mary J, et al. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association PMID:19883714 | 2010 | 1 | none stated | not extracted yet |
| (−)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRβ and IGF-1R Yasuda 2009 · Yasuda Yoichi, Shimizu Masahito, et al. · Chemico-Biological Interactions DOI:10.1016/j.cbi.2009.07.015 | 2009 | 1 | none stated | not extracted yet |
| Epigallocatechin-3-gallate improves nonalcoholic steatohepatitis model mice expressing nuclear sterol regulatory element binding protein-1c in… Ueno 2009 · Ueno · International Journal of Molecular Medicine DOI:10.3892/ijmm_00000200 | 2009 | 1 | none stated | not extracted yet |
| [Epigallocatechin-3-gallate inhibits growth and angiogenesis of gastric cancer and its molecular mechanism]. Zhu 2009 · Zhu Bao-He, Zhan Wen-Hua, et al. · Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery PMID:19145512 | 2009 | 1 | none stated | not extracted yet |
| Epigallocatechin-3-gallate improves nonalcoholic steatohepatitis model mice expressing nuclear sterol regulatory element binding protein-1c in… Ueno 2009 · Ueno Takato, Torimura Takuji, et al. · International journal of molecular medicine PMID:19513529 | 2009 | 1 | none stated | not extracted yet |
| (-)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRbeta and IGF-1R. Yasuda 2009 · Yasuda Yoichi, Shimizu Masahito, et al. · Chemico-biological interactions PMID:19646978 | 2009 | 1 | none stated | not extracted yet |
| Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid Ran 2008 · Ran Zhi Hua, Chen Chi, et al. · Biomedicine & Pharmacotherapy DOI:10.1016/j.biopha.2008.02.002 | 2008 | 1 | none stated | not extracted yet |
| Epigallocatechin gallate attenuates experimental non‐alcoholic steatohepatitis induced by high fat diet Kuzu 2008 · Kuzu Nalan, Bahcecioglu Ibrahim Halil, et al. · Journal of Gastroenterology and Hepatology DOI:10.1111/j.1440-1746.2007.05052.x | 2008 | 1 | none stated | not extracted yet |
| (−)-Epigallocatechin Gallate Suppresses Azoxymethane-Induced Colonic Premalignant Lesions in Male C57BL/KsJ-<i>db/db</i> Mice Shimizu 2008 · Shimizu Masahito, Shirakami Yohei, et al. · Cancer Prevention Research DOI:10.1158/1940-6207.capr-08-0045 | 2008 | 1 | none stated | not extracted yet |
| Protective Effects of Epigallocatechin Gallate on Colon Preneoplastic Lesions Induced by 2-Amino-3-Methylimidazo(4,5-f)Quinoline in Mice Yuan 2008 · Yuan Jun-Hua, Li Yan-Qing, et al. · Molecular Medicine DOI:10.2119/2007-00050.yuan | 2008 | 1 | none stated | not extracted yet |
| Epigallocatechin gallate attenuates experimental non-alcoholic steatohepatitis induced by high fat diet. Kuzu 2008 · Kuzu Nalan, Bahcecioglu Ibrahim Halil, et al. · Journal of gastroenterology and hepatology PMID:17683497 | 2008 | 1 | none stated | not extracted yet |
| Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid. Ran 2008 · Ran Zhi Hua, Chen Chi, et al. · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie PMID:18325726 | 2008 | 1 | none stated | not extracted yet |
| Protective effects of epigallocatechin gallate on colon preneoplastic lesions induced by 2-amino-3-methylimidazo[4,5-f ] quinoline in mice. Yuan 2008 · Yuan Jun-Hua, Li Yan-Qing, et al. · Molecular medicine (Cambridge, Mass.) PMID:18596869 | 2008 | 1 | none stated | not extracted yet |
| (-)-Epigallocatechin gallate suppresses azoxymethane-induced colonic premalignant lesions in male C57BL/KsJ-db/db mice. Shimizu 2008 · Shimizu Masahito, Shirakami Yohei, et al. · Cancer prevention research (Philadelphia, Pa.) PMID:19138973 | 2008 | 1 | none stated | not extracted yet |
| Green tea polyphenol epigallocatechin-3-gallate inhibits oxidative damage and preventive effects on carbon tetrachloride–induced hepatic fibrosis Zhen 2007 · Zhen Mao-chuan, Wang Qian, et al. · The Journal of Nutritional Biochemistry DOI:10.1016/j.jnutbio.2006.12.016 | 2007 | 1 | none stated | not extracted yet |
| Green tea polyphenol epigallocatechin-3-gallate inhibits oxidative damage and preventive effects on carbon tetrachloride-induced hepatic fibrosis. Zhen 2007 · Zhen Mao-Chuan, Wang Qian, et al. · The Journal of nutritional biochemistry PMID:17481882 | 2007 | 1 | none stated | not extracted yet |
| Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: Genotoxicity Isbrucker 2006 · Isbrucker R.A., Bausch J., et al. · Food and Chemical Toxicology DOI:10.1016/j.fct.2005.07.005 | 2006 | 1 | none stated | not extracted yet |
| Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: Dermal, acute and short-term toxicity studies Isbrucker 2006 · Isbrucker R.A., Edwards J.A., et al. · Food and Chemical Toxicology DOI:10.1016/j.fct.2005.11.003 | 2006 | 1 | none stated | not extracted yet |
| Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity. Isbrucker 2006 · Isbrucker R A, Bausch J, et al. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association PMID:16364532 | 2006 | 1 | none stated | not extracted yet |
| Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies. Isbrucker 2006 · Isbrucker R A, Edwards J A, et al. · Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association PMID:16387402 | 2006 | 1 | none stated | not extracted yet |
| Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane Ohishi 2002 · Ohishi Tomokazu, Kishimoto Yosuke, et al. · Cancer Letters DOI:10.1016/s0304-3835(01)00767-4 | 2002 | 1 | none stated | not extracted yet |
| Synergistic effects of (-)-epigallocatechin gallate with sulindac against colon carcinogenesis of rats treated with azoxymethane. Ohishi 2002 · Ohishi Tomokazu, Kishimoto Yosuke, et al. · Cancer letters PMID:11809530 | 2002 | 1 | none stated | not extracted yet |
| EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells Jung 2001 · Jung Y D, Kim M S, et al. · British Journal of Cancer DOI:10.1054/bjoc.2000.1691 | 2001 | 1 | none stated | not extracted yet |
| EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. Jung 2001 · Jung Y D, Kim M S, et al. · British journal of cancer PMID:11259102 | 2001 | 1 | none stated | not extracted yet |
| Dermal toxicity of topical (−)epigallocatechin-3-gallate in BALB/c and SKH1 mice Stratton 2000 · Stratton Steven P., Bangert Jerry L., et al. · Cancer Letters DOI:10.1016/s0304-3835(00)00498-5 | 2000 | 1 | none stated | not extracted yet |
| Dermal toxicity of topical (-)epigallocatechin-3-gallate in BALB/c and SKH1 mice. Stratton 2000 · Stratton S P, Bangert J L, et al. · Cancer letters PMID:10940508 | 2000 | 1 | none stated | not extracted yet |
| Inhibitory Effect of (—)‐Epigallocatechin Gallate on Carcinogenesis with N‐Ethyl‐N′‐nitro‐N‐nitrosoguanidine in Mouse Duodenum Fujita 1989 · Fujita Yoshihiro, Yamane Tetsuro, et al. · Japanese Journal of Cancer Research DOI:10.1111/j.1349-7006.1989.tb01666.x | 1989 | 1 | none stated | not extracted yet |
| Inhibitory effect of (-)-epigallocatechin gallate on carcinogenesis with N-ethyl-N'-nitro-N-nitrosoguanidine in mouse duodenum. Fujita 1989 · Fujita Y, Yamane T, et al. · Japanese journal of cancer research : Gann PMID:2503469 | 1989 | 1 | none stated | not extracted yet |
| Wei 2014 DOI:10.11847/zgggws2014-30-03-16 | NR | 1 | none stated | not extracted yet |
| Xu 2025 DOI:10.12449/jch250716 | NR | 1 | none stated | not extracted yet |
| Li 2023 DOI:10.13386/j.issn1002-0306.2022080331 | NR | 1 | none stated | not extracted yet |
| Gang 2007 DOI:10.3971/j.issn.1000-8578.175 | NR | 1 | none stated | not extracted yet |
| Jiang 2020 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Song 2023 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Wang 2010 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Xiao 2011 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Yang 2012 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |
| Yuan 2010 matched by author and year (probable) | NR | 1 | none stated | not extracted yet |