Studies
Primary studies
26,293 studies included by 1,022 non-Cochrane dental reviews extracted from full text, one record per study, so a study included by several reviews is counted once. Most are randomized trials; etiology and diagnostic reviews also include observational and accuracy studies. Cochrane reviews and reviews with only their headline outcomes do not list their included studies here yet.
ReviewStudies included by Do Adjunctive Therapies with Natural Products Improve Periodontal Clinical Parameters After Non-Surgical Treatment? A Systematic Review…. Show all studies
| Study | Year | Reviews | Review outcomes linked | Trial data |
|---|---|---|---|---|
| Comparative evaluation of herbal gel as an adjunct to nonsurgical periodontal therapy in Stage III periodontitis: A randomized split-mouth clinical… Rathod et al., 2024 · Rathod Surekha Ramrao, Kaule Supriya Suresh, et al. · Journal of Indian Society of Periodontology PMID:40313342 | 2024 | 1 | none stated | not extracted yet |
| Comparative assessment of Omega-3 and CoQ10 as adjuncts to periodontal therapy and total antioxidant capacity of saliva in patients with chronic… Farahmand et al., 2024 · Farahmand Amirhossein, Talebi Marjan, et al. · The Saudi dental journal PMID:40952889 | 2024 | 1 | none stated | not extracted yet |
| Clinical and bacterial periodontal parameters with methylene blue-loaded nanoparticles incorporated in a natural plant-based vehicle for the… Elsadek et al., 2023 · Elsadek Mohamed Farouk, Almoajel Alia · Photodiagnosis and Photodynamic Therapy DOI:10.1016/j.pdpdt.2023.103586 | 2023 | 1 | none stated | not extracted yet |
| The effect of oolong tea as an adjunct to nonsurgical management of chronic periodontitis: A randomized controlled clinical trial Nafade et al., 2022 · Nafade Sonal, Agnihotri Rupali, et al. · Journal of Herbmed Pharmacology DOI:10.34172/jhp.2022.30 | 2022 | 1 | none stated | not extracted yet |
| Clinical and antioxidant efficacy of 4% mangosteen gel as a local drug delivery in the treatment of chronic periodontitis: A placebo-controlled,… Manjunatha et al., 2022 · Manjunatha Vinayaka Ambujakshi, Vemanaradhya Gayathri Gunjiganur, et al. · Dental and medical problems PMID:35359035 | 2022 | 1 | none stated | not extracted yet |
| Antioxidant effect of spirulina in chronic periodontitis. Kaipa et al., 2022 · Kaipa Vinay Rama Krishna, Asif Shaik Mohammed, et al. · Medicine PMID:36550811 | 2022 | 1 | none stated | not extracted yet |
| Efficacy of 3% Psidium guajava local drug delivery in the treatment of chronic periodontitis: A randomized controlled trial Sharma et al., 2021 · Manohar Sharma H, Deepika PC, et al. · Journal of International Oral Health DOI:10.4103/jioh.jioh_249_20 | 2021 | 1 | none stated | not extracted yet |
| Intrapocket application of tea tree oil gel in the treatment of stage 2 periodontitis. Taalab et al., 2021 · Taalab Maha R, Mahmoud Sabah Abdelhady, et al. · BMC oral health PMID:33952216 | 2021 | 1 | none stated | not extracted yet |
| Efficacy of Complex Phytoadaptogens as an Adjunct to Non-surgical Treatment of Chronic Periodontitis: A Randomized Clinical Trial. Dzampaeva et al., 2021 · Dzampaeva Zhanna Valerevna, Datieva Fatima Sergeevna, et al. · Journal of International Society of Preventive & Community Dentistry PMID:34268198 | 2021 | 1 | none stated | not extracted yet |
| Clinical efficacy of grape seed extract as an adjuvant to scaling and root planing in treatment of periodontal pockets. Das et al., 2021 · Das M, Das A C, et al. · Journal of biological regulators and homeostatic agents PMID:34281305 | 2021 | 1 | none stated | not extracted yet |
| Semelil as Adjunctive Therapy in Chronic Periodontitis: A Preliminary Randomized Controlled Clinical Study. Aslroosta et al., 2021 · Aslroosta Hoori, Paknejad Mojgan, et al. · Iranian journal of pharmaceutical research : IJPR PMID:34400963 | 2021 | 1 | none stated | not extracted yet |
| Clinical Evaluation of the Effects of Topical Indocyanine-green Mediated Photosensitiser vs Aloe Vera Gel as Adjunct Therapy to Scaling and Root… Qamar et al., 2021 · Qamar Zeeshan, Almohana Salah Abdalkreem, et al. · Oral health & preventive dentistry PMID:34585874 | 2021 | 1 | none stated | not extracted yet |
| Clinical and Microbiological Outcomes of Topical Aloe Vera Gel vs. Photochemotherapy as an Adjunct to Non-surgical Periodontal Treatment in… Elsadek et al., 2020 · Elsadek Mohamed Farouk, Ahmed Badreldin Mohamed, et al. · Planta Medica International Open DOI:10.1055/a-1159-0738 | 2020 | 1 | none stated | not extracted yet |
| The Effects of Salvia officinalis Gel as an Adjunct to Scaling and Root Planning in Patients with Periodontitis (Clinical and Immunological Study) Aljuboori & Mahmood, 2020 · Aljuboori Ismael W., Mahmood Maha Sh. · International Journal of Drug Delivery Technology DOI:10.25258/ijddt.10.2.8 | 2020 | 1 | none stated | not extracted yet |
| Antimicrobial efficacy of indocyanine green-mediated photodynamic therapy compared with Salvadora persica gel application in the treatment of… Niazi et al., 2020 · Niazi Fayez Hussain, Noushad Mohammed, et al. · Photodiagnosis and photodynamic therapy PMID:31978565 | 2020 | 1 | none stated | not extracted yet |
| Effect of topical administration of propolis in chronic periodontitis. Nakao et al., 2020 · Nakao Ryoma, Senpuku Hidenobu, et al. · Odontology PMID:32112365 | 2020 | 1 | none stated | not extracted yet |
| Efficacy of Curcumin Gel on Zinc, Magnesium, Copper, IL-1β, and TNF-α in Chronic Periodontitis Patients. Mohammad, 2020 · Mohammad Chenar Anwar · BioMed research international PMID:33083489 | 2020 | 1 | none stated | not extracted yet |
| Lycopene solid lipid microparticles with enhanced effect on gingival crevicular fluid protein carbonyl as a biomarker of oxidative stress in… Tawfik et al., 2019 · Tawfik Maie S, Abdel-Ghaffar Khaled A, et al. · Journal of liposome research PMID:30633595 | 2019 | 1 | none stated | not extracted yet |
| Antimicrobial photodynamic therapy (aPDT) with curcumin and LED, as an enhancement to scaling and root planing in the treatment of residual pockets… Ivanaga et al., 2019 · Ivanaga Camila Ayumi, Miessi Daniela Maria Janjacomo, et al. · Photodiagnosis and photodynamic therapy PMID:31301434 | 2019 | 1 | none stated | not extracted yet |
| Impact of resveratrol supplementation on inflammatory, antioxidant, and periodontal markers in type 2 diabetic patients with chronic periodontitis. Javid et al., 2019 · Javid Ahmad Zare, Hormoznejad Razie, et al. · Diabetes & metabolic syndrome PMID:31405706 | 2019 | 1 | none stated | not extracted yet |
| Efficacy of a mouthwash containing essential oils and curcumin as an adjunct to nonsurgical periodontal therapy among rheumatoid arthritis patients… Anusha et al., 2019 · Anusha Divvi, Chaly Preetha Elizabeth, et al. · Indian journal of dental research : official publication of Indian Society for Dental Research PMID:31745043 | 2019 | 1 | none stated | not extracted yet |
| The effects of ginger supplementation on inflammatory, antioxidant, and periodontal parameters in type 2 diabetes mellitus patients with chronic… Zare Javid et al., 2019 · Zare Javid Ahmad, Bazyar Hadi, et al. · Diabetes, metabolic syndrome and obesity : targets and therapy PMID:32021341 | 2019 | 1 | none stated | not extracted yet |
| Efficacy of grape seed extract gel in the treatment of chronic periodontitis: A randomized clinical study. Rayyan et al., 2018 · Rayyan Mohammad, Terkawi Tammam, et al. · Journal of investigative and clinical dentistry PMID:29349878 | 2018 | 1 | none stated | not extracted yet |
| Effects of Chicory Leaf Extract on Serum Oxidative Stress Markers, Lipid Profile and Periodontal Status in Patients With Chronic Periodontitis. Babaei et al., 2018 · Babaei Hossein, Forouzandeh Fahimeh, et al. · Journal of the American College of Nutrition PMID:29558323 | 2018 | 1 | none stated | not extracted yet |
| Impact of green tea intake on clinical improvement in chronic periodontitis: A randomized clinical trial. Taleghani et al., 2018 · Taleghani F, Rezvani G, et al. · Journal of stomatology, oral and maxillofacial surgery PMID:29723659 | 2018 | 1 | none stated | not extracted yet |
| The Impact of Resveratrol Supplementation on Blood Glucose, Insulin, Insulin Resistance, Triglyceride, and Periodontal Markers in Type 2 Diabetic… Zare Javid et al., 2017 · Zare Javid Ahmad, Hormoznejad Razie, et al. · Phytotherapy research : PTR PMID:27807887 | 2017 | 1 | none stated | not extracted yet |
| Clinical and microbiological efficacy of 4% Garcinia mangostana L. pericarp gel as local drug delivery in the treatment of chronic periodontitis: A… Mahendra et al., 2017 · Mahendra Jaideep, Mahendra Little, et al. · Journal of investigative and clinical dentistry PMID:28321995 | 2017 | 1 | none stated | not extracted yet |
| Subgingival Irrigation with a Solution of 20% Propolis Extract as an Adjunct to Non-Surgical Periodontal Treatment: A Preliminary Study. Andrade et al., 2017 · Andrade Dennia Perez de, Carvalho Isabel Chaves Silva, et al. · Journal of the International Academy of Periodontology PMID:31473730 | 2017 | 1 | none stated | not extracted yet |
| Clinical effect of locally delivered gel containing green tea extract as an adjunct to non-surgical periodontal treatment. Rattanasuwan et al., 2016 · Rattanasuwan Kanyawat, Rassameemasmaung Supanee, et al. · Odontology PMID:25523604 | 2016 | 1 | none stated | not extracted yet |
| Adjunctive Local Delivery of Aloe Vera Gel in Patients With Type 2 Diabetes and Chronic Periodontitis: A Randomized, Controlled Clinical Trial. Pradeep et al., 2016 · Pradeep A R, Garg Vibhuti, et al. · Journal of periodontology PMID:26447752 | 2016 | 1 | none stated | not extracted yet |
| Effect of Subgingivally Delivered 10% Emblica officinalis Gel as an Adjunct to Scaling and Root Planing in the Treatment of Chronic Periodontitis -… Grover et al. 2016 · Grover Shilpa, Tewari Shikha, et al. · Phytotherapy research : PTR PMID:26914986 | 2016 | 1 | none stated | not extracted yet |
| Green Tea Intake as an Adjunct to Mechanical Periodontal Therapy for the Management of Mild to Moderate Chronic Periodontitis: A Randomized… Chopra et al., 2016 · Chopra Aditi, Thomas Betsy S, et al. · Oral health & preventive dentistry PMID:27175448 | 2016 | 1 | none stated | not extracted yet |
| Adjunctive use of essential oils following scaling and root planing -a randomized clinical trial. Azad et al. 2016 · Azad Mohammad Fallah, Schwiertz Andreas, et al. · BMC complementary and alternative medicine PMID:27266517 | 2016 | 1 | none stated | not extracted yet |
| Propolis Improves Periodontal Status and Glycemic Control in Patients With Type 2 Diabetes Mellitus and Chronic Periodontitis: A Randomized Clinical… El-Sharkawy et al., 2016 · El-Sharkawy Hesham M, Anees Mohamed M, et al. · Journal of periodontology PMID:27468795 | 2016 | 1 | none stated | not extracted yet |
| Comparative evaluation of the efficacy of curcumin gel with and without photo activation as an adjunct to scaling and root planing in the treatment… Sreedhar et al., 2015 · Sreedhar Annaji, Sarkar Indranil, et al. · Journal of natural science, biology, and medicine PMID:26604595 | 2015 | 1 | none stated | not extracted yet |
| Comparative evaluation of the efficacy of two controlled release devices: Chlorhexidine chips and indigenous curcumin based collagen as local drug… Gottumukkala et al. 2013 · Gottumukkala Sruthima N V S, Sudarshan Sabitha, et al. · Contemporary clinical dentistry PMID:24963242 | 2014 | 1 | none stated | not extracted yet |
| Effects of Ginkgo biloba extract on periodontal pathogens and its clinical efficacy as adjuvant treatment. Cheng et al., 2014 · Cheng Qian, Gao Wei-min, et al. · Chinese journal of integrative medicine PMID:25098260 | 2014 | 1 | none stated | not extracted yet |
| Health from the hive: propolis as an adjuvant in the treatment of chronic periodontitis - a clinicomicrobiologic study. Sanghani et al. 2014 · Sanghani Nehal N, Bm Shivaprasad, et al. · Journal of clinical and diagnostic research : JCDR PMID:25386520 | 2014 | 1 | none stated | not extracted yet |
| A randomized clinical trial on the clinical and microbiological efficacy of a xanthan gel with chlorhexidine for subgingival use. Matesanz et al. 2013 · Matesanz Paula, Herrera David, et al. · Clinical oral investigations PMID:22350036 | 2013 | 1 | none stated | not extracted yet |
| Thermo-reversible green tea catechin gel for local application in chronic periodontitis: a 4-week clinical trial. Chava & Vedula 2013 · Chava Vijay Kumar, Vedula Bhargavi Devi · Journal of periodontology PMID:23121459 | 2013 | 1 | none stated | not extracted yet |
| The adjunctive use of systemic antioxidant therapy (lycopene) in nonsurgical treatment of chronic periodontitis: a short-term evaluation. Arora et al. 2013 · Arora Nupur, Avula Haritha, et al. · Quintessence international (Berlin, Germany : 1985) PMID:23479592 | 2013 | 1 | none stated | not extracted yet |
| Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a… Chapple et al., 2012 · Chapple Iain L C, Milward Michael R, et al. · Journal of clinical periodontology PMID:22093005 | 2012 | 1 | none stated | not extracted yet |
| Honeybee propolis extract in periodontal treatment: a clinical and microbiological study of propolis in periodontal treatment. Coutinho A. 2012 · Coutinho Amita · Indian journal of dental research : official publication of Indian Society for Dental Research PMID:22945731 | 2012 | 1 | none stated | not extracted yet |
| Topical application of Garcinia mangostana L. pericarp gel as an adjunct to periodontal treatment. Rassameemasmaung et al., 2008 · Rassameemasmaung Supanee, Sirikulsathean Anongporn, et al. · Complementary therapies in medicine PMID:19186342 | 2008 | 1 | none stated | not extracted yet |
| The acute effects of central- and peripheral-acting dopamine antagonists on plasma HVA in schizophrenic patients. Rassameemasmaung et al., 2008 · Konicki P E, Owen R R, et al. · Life sciences PMID:2008157 | 1991 | 1 | none stated | not extracted yet |
| Extrahepatic bile duct growth in mice repeatedly injected with human normal serum, IgA-deficient serum or purified secretory IgA. El-Sharkawy et al., 2010 · Solbreux P M, Maldague P, et al. · Hepatology (Baltimore, Md.) PMID:2010169 | 1991 | 1 | none stated | not extracted yet |
| HIV testing in women with vaginal candidiasis. Coutinho A. 2012 · DeHart D J · The American journal of medicine PMID:2012101 | 1991 | 1 | none stated | not extracted yet |
| Senile accommodative degeneration (SAD). Patel et al. 2012 · Jampolsky A · American journal of ophthalmology PMID:2012156 | 1991 | 1 | none stated | not extracted yet |
| Interleukin-1 gene expression in rabbit vascular tissue in vivo. Chapple et al., 2012 · Clinton S K, Fleet J C, et al. · The American journal of pathology PMID:2012168 | 1991 | 1 | none stated | not extracted yet |
| Early afterdepolarizations and triggered activity in rabbit cardiac Purkinje fibers recovering from ischemic-like conditions. Role of acidosis. Chava & Vedula 2013 · Rozanski G J, Witt R C · Circulation PMID:2013152 | 1991 | 1 | none stated | not extracted yet |