Primary study · included by 3 reviews

Arthrocentesis, Injectable Platelet-Rich Plasma and Combination of Both Protocols of Temporomandibular Joint Disorders Management: A Single-Blinded Randomized Clinical Trial.

Abbadi 2022 · Abbadi Wael, Kara Beit Zafin, Al-Khanati Nuraldeen M · Cureus · 2022

Included by

Advanced, pharmacological and complementary interventions for chronic or recurrent orofacial pain conditions: a systematic evidence map with selective meta-analyses.
Non-Cochrane · intervention · 2026 · cited as Abbadi 2022 · Reference list (ref 54); Supplementary Table 4
Outcome this study informsPooled effectEvidenceCertainty
Pain intensity
Injectables / intra-articular procedures vs Active comparator · Long-term (more than 12 weeks)
SMD -0.46 [-0.85, -0.08]9 studies · 272 participantsGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD 0.07 [-1.38, 1.52]6 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.70 [-1.21, -0.19]NRGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.43 [-0.88, 0.03]6 studiesGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD 0.22 [-1.21, 1.65]6 studiesGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD -0.02 [-1.48, 1.44]6 studiesGRADE not reported
Pain intensity
Injectables / intra-articular procedures vs Active comparator · Long-term (more than 12 weeks)
SMD -0.44 [-0.66, -0.21]9 studies · 272 participantsGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.44 [-0.80, -0.08]6 studiesGRADE not reported
Jaw function
Injectables / intra-articular procedures vs Active comparator · Long-term (more than 12 weeks)
MD -0.32 [-1.95, 1.32]7 studies · 221 participantsGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.53 [-0.92, -0.15]8 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.42 [-0.84, -0.01]8 studiesGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD -0.67 [-2.86, 1.51]6 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.28 [-0.50, -0.06]6 studiesGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD -0.32 [-1.95, 1.32]7 studies · 221 participantsVery low
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.48 [-0.90, -0.06]8 studiesGRADE not reported
Pain intensity
Injectables / intra-articular procedures vs Active comparator · Short-term (immediate to 4 weeks)
SMD -0.40 [-0.73, -0.08]7 studies · 201 participantsGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.40 [-0.78, -0.03]6 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.46 [-0.85, -0.08]9 studies · 272 participantsVery low
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.53 [-1.05, -0.01]8 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.40 [-0.73, -0.08]7 studies · 201 participantsLow
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.55 [-0.88, -0.22]8 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.31 [-0.67, 0.06]8 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.46 [-0.81, -0.11]6 studiesGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD -1.57 [-4.99, 1.86]NRGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD -0.80 [-3.21, 1.61]6 studiesGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD -0.69 [-2.93, 1.55]6 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.42 [-0.79, -0.05]6 studiesGRADE not reported
Jaw function
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
MD -0.57 [-1.97, 0.83]6 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.40 [-0.78, -0.01]6 studiesGRADE not reported
Jaw function
Injectables / intra-articular procedures vs Active comparator · Long-term (more than 12 weeks)
MD -0.14 [-1.14, 0.86]7 studies · 221 participantsGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.46 [-0.88, -0.04]8 studiesGRADE not reported
Pain intensity
Injectables / intra-articular procedures vs Active comparator · Short-term (immediate to 4 weeks)
SMD -0.41 [-0.67, -0.14]7 studies · 201 participantsGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.47 [-0.89, -0.05]8 studiesGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Short-term (immediate post-intervention to 4 weeks)
SMD -0.37 [-0.89, 0.15]NRGRADE not reported
Pain intensity
Injectables or intra-articular procedures vs Active comparator · Long-term (>12 weeks)
SMD -0.42 [-0.83, -0.01]8 studiesGRADE not reported
Outcome this study informsPooled effectEvidenceCertainty
Pain intensity (VAS)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -1.609 [-5.033, 1.816]NRGRADE not reported
Maximum mouth opening (MMO)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
SMD -0.67 [-1.14, -0.20]14 studies · 549 participantsLow
Pain intensity (VAS)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -0.25 [-1.09, 0.59]26 studies · 947 participantsVery low
Maximum mouth opening (MMO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.067 [-0.156, 0.021]NRGRADE not reported
Pain intensity (VAS)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.028 [-0.125, 0.069]NRGRADE not reported
Maximum mouth opening (MMO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.681 [-3.831, 2.470]NRGRADE not reported
Efficacy of combined therapies on degenerative joint disease of the temporomandibular joint: A systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Abbadi 2022 · Supplement mmc1 Appendix C section A (RCTs in meta-analysis), A9

The review does not say which of its outcomes this study informs.

3 including reviews in total.