Primary study · included by 3 reviews

Intra-articular injection of hyaluronic acid versus platelet-rich plasma following single puncture arthrocentesis for the management of internal derangement of TMJ: A double-blinded randomised controlled trial.

Dasukil 2022 · Dasukil Saubhik, Arora Geetanjali, Boyina Kiran Kumar, et al. · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · 2022

Included by

Efficacy and Safety of Intra-Articular Therapies for Temporomandibular Disorders: A Systematic Review and Meta-Analysis.
Non-Cochrane · intervention · 2026 · cited as Dasukil 2022 · Table 1; reference list

The review does not say which of its outcomes this study informs.

Outcome this study informsPooled effectEvidenceCertainty
Pain intensity (VAS)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -1.609 [-5.033, 1.816]NRGRADE not reported
Maximum mouth opening (MMO)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
SMD -0.67 [-1.14, -0.20]14 studies · 549 participantsLow
Pain intensity (VAS)
TMJ arthrocentesis, alone or with adjunctive intra-articular agents vs Other therapeutic modalities (conservative therapy, intra-articular injections, arthroscopy, alternative arthrocentesis protocols) · Follow-up from 1 month to 5 years across trials (mean 53 weeks)
MD -0.25 [-1.09, 0.59]26 studies · 947 participantsVery low
Maximum mouth opening (MMO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.067 [-0.156, 0.021]NRGRADE not reported
Pain intensity (VAS)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.028 [-0.125, 0.069]NRGRADE not reported
Maximum mouth opening (MMO)
Temporomandibular joint arthrocentesis, alone or with adjunctive intra-articular agents vs Other treatments: conservative therapy (splints, physiotherapy, drugs), intra-articular injections, arthroscopy, or alternative arthrocentesis protocols
Meta-regression coefficient (beta) -0.681 [-3.831, 2.470]NRGRADE not reported

The review does not say which of its outcomes this study informs.

3 including reviews in total.