Primary study · included by 3 reviews
Stem cell therapy for reconstruction of alveolar cleft and trauma defects in adults: A randomized controlled, clinical trial.
Bajestan 2017 · Bajestan Mona N, Rajan Archana, Edwards Sean P, et al. · Clinical implant dentistry and related research · 2017
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Implant success rate Mesenchymal stem cell (MSC)-based bone regeneration (MSC with biomaterial or cellular allograft) vs Bone regeneration without stem cells (e.g., biomaterial or autograft alone, blood clot, particulate allograft) | log RR -0.03 [-0.09, 0.04] | 4 studies | GRADE not reported |
Implant success rate Mesenchymal stem cell (MSC)-based bone regeneration (MSC with biomaterial or cellular allograft) vs Bone regeneration without stem cells (e.g., biomaterial or autograft alone, blood clot, particulate allograft) | log RR -0.03 [-0.10, 0.04] | 4 studies | GRADE not reported |
Implant success rate Mesenchymal stem cell (MSC)-based bone regeneration (MSC with biomaterial or cellular allograft) vs Bone regeneration without stem cells (e.g., biomaterial or autograft alone, blood clot, particulate allograft) · Follow-up 3 to 12 months | RR 0.98 [0.94, 1.03] | 5 studies · 222 implants participants | Moderate |
Bone regeneration (continuous) Mesenchymal stem cell (MSC)-based bone regeneration vs Conventional grafting without stem cells (DBBM, autograft, allograft or blood clot) | SMD -0.83 [-1.37, -0.30] | 2 studies | High |
Implant success rate Mesenchymal stem cell (MSC)-based bone regeneration (MSC with biomaterial or cellular allograft) vs Bone regeneration without stem cells (e.g., biomaterial or autograft alone, blood clot, particulate allograft) | log RR -0.01 [-0.06, 0.03] | 4 studies | GRADE not reported |
Implant success rate Mesenchymal stem cell (MSC)-based bone regeneration (MSC with biomaterial or cellular allograft) vs Bone regeneration without stem cells (e.g., biomaterial or autograft alone, blood clot, particulate allograft) | log RR -0.03 [-0.10, 0.04] | 4 studies | GRADE not reported |
Bone regeneration (bone neoformation, continuous) Mesenchymal stem cell (MSC)-based bone regeneration (MSC with biomaterial or cellular allograft) vs Bone regeneration without stem cells (e.g., biomaterial or autograft alone, blood clot, particulate allograft) | SMD -0.84 [-1.36, -0.32] | 2 studies · 60 participants | High |
Implant success rate Mesenchymal stem cell (MSC)-based bone regeneration (MSC with biomaterial or cellular allograft) vs Bone regeneration without stem cells (e.g., biomaterial or autograft alone, blood clot, particulate allograft) | log RR -0.00 [-0.05, 0.04] | 4 studies | GRADE not reported |
The review does not say which of its outcomes this study informs.
The review does not say which of its outcomes this study informs.
3 including reviews in total.